CLDN7

Gene Symbol	CLDN7
Entrez Gene	1366
Alt Symbol	CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Species	Human
Gene Type	protein-coding
Description	claudin 7
Other Description	claudin-7|clostridium perfringens enterotoxin receptor-like 2
Swissprots	Q9BVN0 Q7Z4Y7 Q6IPN3 B2R9X7 O95471 D3DTP0
Accessions	EAW90228 EAW90229 O95471 AF093823 AAP97219 AJ011497 CAA09626 AK225418 AK313958 BAG36674 BC001055 AAH01055 BC071844 AAH71844 BM818537 BT006829 AAP35475 CV575841 NM_001185022 NP_001171951 NM_001185023 NP_001171952 NM_001307 NP_001298
Function	Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Note=Co- localizes with EPCAM at the lateral cell membrane and tight junction.
Tissue Specificity	Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions. {ECO:0000269|PubMed:12673207, ECO:0000269|PubMed:14502431}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

claudin-7 (C-15) - sc-17670 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

claudin-7 (FL-211) - sc-33532 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Claudin 7 (phospho Y210) antibody - ab78198 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Claudin 7 antibody - ab27487 from Abcam Prices $398.00 Sizes 500 µl Host Rabbit Clonality Polyclonal

Anti-Claudin 7 antibody - ab79481 from Abcam Prices $378.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Claudin 7 antibody - ab95221 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Claudin 7 antibody - ab53044 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Claudin 7 antibody, prediluted - ab27488 from Abcam Prices $376.00 Sizes 7 ml Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209, Biotin) - LS-C221806 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody - LS-C192739 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209, APC) - LS-C221807 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209, FITC) - LS-C221808 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209, Azide-free, HRP) - LS-C221810 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209, PE) - LS-C221813 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody - LS-C309930 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209) - LS-C320430 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (phospho-Tyr210) - LS-C198813 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa107-120) IHC-plus™ - LS-B798 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (Ser204) - LS-C177794 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (Pro202) - LS-C175970 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa179-209) - LS-C168819 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa162-211) IHC-plus™ - LS-B7590 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody - LS-C331839 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (aa162-211) IHC-plus™ - LS-B7594 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CLDN7 / Claudin 7 Antibody (C-Terminus) IHC-plus™ - LS-B2918 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Mouse Clonality Monoclonal

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