CLDN7

Gene Symbol CLDN7
Entrez Gene 1366
Alt Symbol CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Species Human
Gene Type protein-coding
Description claudin 7
Other Description claudin-7|clostridium perfringens enterotoxin receptor-like 2
Swissprots Q9BVN0 Q7Z4Y7 Q6IPN3 B2R9X7 O95471 D3DTP0
Accessions EAW90228 EAW90229 O95471 AF093823 AAP97219 AJ011497 CAA09626 AK225418 AK313958 BAG36674 BC001055 AAH01055 BC071844 AAH71844 BM818537 BT006829 AAP35475 CV575841 NM_001185022 NP_001171951 NM_001185023 NP_001171952 NM_001307 NP_001298
Function Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Note=Co- localizes with EPCAM at the lateral cell membrane and tight junction.
Tissue Specificity Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions. {ECO:0000269|PubMed:12673207, ECO:0000269|PubMed:14502431}.
Top Pathways Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

claudin-7 CRISPR/Cas9 KO Plasmid (h) - sc-403462 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 HDR Plasmid (h) - sc-403462-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 Double Nickase Plasmid (h) - sc-403462-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 Double Nickase Plasmid (h2) - sc-403462-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 CRISPR Activation Plasmid (h) - sc-403462-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 CRISPR Activation Plasmid (h2) - sc-403462-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 Lentiviral Activation Particles (h) - sc-403462-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 Lentiviral Activation Particles (h2) - sc-403462-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

claudin-7 siRNA (h) - sc-43048 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

claudin-7 shRNA Plasmid (h) - sc-43048-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

claudin-7 shRNA (h) Lentiviral Particles - sc-43048-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU145621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6191 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6191 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLDN7 siRNA (Human) - CRH0956 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Claudin-7 RNAi - H00001366-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CLDN7 - MBS8205578 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLDN7 (NM_001307.5) - SHH264833 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLDN7 siRNA - orb261458 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLDN7 shRNA Plasmid (Human) - CHH0956 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLDN7 miRNA 3'UTR clone - MiUTR3H-10427 from Creative biogene

Species Reactivities Human
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