CLDN7

Gene Symbol	CLDN7
Entrez Gene	1366
Alt Symbol	CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Species	Human
Gene Type	protein-coding
Description	claudin 7
Other Description	claudin-7|clostridium perfringens enterotoxin receptor-like 2
Swissprots	Q9BVN0 Q7Z4Y7 Q6IPN3 B2R9X7 O95471 D3DTP0
Accessions	EAW90228 EAW90229 O95471 AF093823 AAP97219 AJ011497 CAA09626 AK225418 AK313958 BAG36674 BC001055 AAH01055 BC071844 AAH71844 BM818537 BT006829 AAP35475 CV575841 NM_001185022 NP_001171951 NM_001185023 NP_001171952 NM_001307 NP_001298
Function	Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Note=Co- localizes with EPCAM at the lateral cell membrane and tight junction.
Tissue Specificity	Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions. {ECO:0000269|PubMed:12673207, ECO:0000269|PubMed:14502431}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Claudin-7 (CAA09626) VersaClone cDNA - RDC0083 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

CLDN7 - MBS1270823 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC071844

CLDN7 - MBS1275984 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001055

Human CLDN7 cDNA clone(NM_001185023.1) - CDFH003809 from Creative Biomart Species Human Accession NM_001185023.1

Human CLDN7 cDNA clone(NM_001185022.1) - CDFH003810 from Creative Biomart Species Human Accession NM_001185022.1

Human CLDN7 ORF Clone(NM_001185022.1) - CDCR357754 from Creative Biomart Species Human Accession NM_001185022.1

Human CLDN7 ORF Clone(NM_001185022.1) - CDCR357755 from Creative Biomart Species Human Accession NM_001185022.1

Human CLDN7 ORF Clone(NM_001185023.1) - CDCR357756 from Creative Biomart Species Human Accession NM_001185023.1

Human CLDN7 ORF Clone(NM_001185023.1) - CDCR357757 from Creative Biomart Species Human Accession NM_001185023.1

Human CLDN7 ORF Clone(NM_001185022.1) - CDCL159011 from Creative Biomart Species Human Accession NM_001185022.1

Human CLDN7 Gene cDNA clone plasmid - HG11455-M from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11455-ACR from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11455-CY from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid - HG11455-UT from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11455-NY from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11455-ACG from Sino Biological Species Human

Human CLDN7 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11455-M-N from Sino Biological Species Human Accession NM_001307.4

Human Claudin 7 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11455-NF from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-His tag - HG11455-CH from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, N-His tag - HG11455-NH from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11455-NM from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11455-CF from Sino Biological Species Human

Human Claudin 7 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11455-CM from Sino Biological Species Human

Human CLDN7 ORF Clone(NM_001185022.1) - CDCR357754 from Creative biogene Species Human

Human CLDN7 ORF clone (NM_001185023.1) - CDCR047786 from Creative biogene Species Human

Search more