CLDN7

Gene Symbol	CLDN7
Entrez Gene	1366
Alt Symbol	CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Species	Human
Gene Type	protein-coding
Description	claudin 7
Other Description	claudin-7|clostridium perfringens enterotoxin receptor-like 2
Swissprots	Q9BVN0 Q7Z4Y7 Q6IPN3 B2R9X7 O95471 D3DTP0
Accessions	EAW90228 EAW90229 O95471 AF093823 AAP97219 AJ011497 CAA09626 AK225418 AK313958 BAG36674 BC001055 AAH01055 BC071844 AAH71844 BM818537 BT006829 AAP35475 CV575841 NM_001185022 NP_001171951 NM_001185023 NP_001171952 NM_001307 NP_001298
Function	Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Note=Co- localizes with EPCAM at the lateral cell membrane and tight junction.
Tissue Specificity	Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions. {ECO:0000269|PubMed:12673207, ECO:0000269|PubMed:14502431}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Claudin 7 peptide - ab108461 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Claudin 7 full length protein - ab132347 from Abcam Category Protein Source Wheat germ Species Human

Human Claudin 7 protein fragment - ab112275 from Abcam Category Protein Source Wheat germ Species Human

CLDN7 / Claudin 7 Antibody Blocking Peptide - LS-E91 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLDN7 / Claudin 7 Antibody Blocking Peptide - LS-E10956 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLDN7 / Claudin 7 Antibody Blocking Peptide - LS-E11886 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Claudin-7 Partial Recombinant Protein - H00001366-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Claudin-7 Protein - H00001366-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CLDN7-Antibody-C-term-Blocking-peptide - BP10180b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Claudin 7 Blocking Peptide - 33R-3466 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Claudin 7 Blocking Peptide - 33R-3465 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Claudin 7 Blocking Peptide - abx062457 from Abbexa Category Peptide Species Human, Mouse, Rat

Claudin-7 / CLDN7 - H00001366-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Claudin-7 / CLDN7 - H00001366-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Claudin-7 / CLDN7 - H00001366-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Claudin-7 / CLDN7 - H00001366-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLDN7 fusion protein - Ag0159 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CLDN7 - CLDN7-27069TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CLDN7, GST-tagged - CLDN7-11299H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Claudin 7 (CLDN7) - RPF297Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Claudin 7 Blocking Peptide - CBP1263 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Claudin-7 (P202) Peptide - BS1070P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Claudin-7 (S204) Peptide - BS3763P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Claudin-7 Recombinant Protein Antigen - NBP1-85683PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Claudin 7 Blocking Peptide - abx061795 from Abbexa Category Peptide

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