Gene Symbol | TFAP2C |
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Entrez Gene | 7022 |
Alt Symbol | AP2-GAMMA, ERF1, TFAP2G, hAP-2g |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
Other Description | activating enhancer-binding protein 2 gamma|estrogen receptor factor 1|transcription factor AP-2 gamma|transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma)|transcription factor ERF-1 |
Swissprots | O00685 Q9P1X2 Q86V30 B4DWK3 O00730 Q8IVB6 Q92754 |
Accessions | AAN37906 BAC11805 CAC86997 EAW75532 Q92754 AK301572 BAG63065 AK314272 BAG36933 BC035664 AAH35664 BC051829 AAH51829 U85658 AAC51305 X95693 CAA64989 NM_003222 NP_003213 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. {ECO:0000269|PubMed:11694877, ECO:0000269|PubMed:24413532}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:24413532}. |
AP-2γ Antibody - 2320 from Cell Signaling Technology
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AP-2γ (B-9) - sc-377458 from Santa Cruz Biotechnology
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AP-2γ (6E4/4) - sc-12762 from Santa Cruz Biotechnology
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AP-2γ (H-77) - sc-8977 from Santa Cruz Biotechnology
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AP-2γ (AP2g 6E4/4) - sc-53162 from Santa Cruz Biotechnology
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AP-2γ (V-18) - sc-31935 from Santa Cruz Biotechnology
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Anti-AP2 gamma antibody - ab31288 from Abcam
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Anti-AP2 gamma antibody - ab101020 from Abcam
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Anti-AP2 gamma antibody - ab136001 from Abcam
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Anti-AP2 gamma antibody [9] - ab87475 from Abcam
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Anti-AP2 gamma antibody [EP2692Y] - ab76007 from Abcam
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Anti-AP2 gamma antibody [EP2693Y] - ab75992 from Abcam
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Anti-TFAP2C / AP2 Gamma Antibody (aa252-301) IHC-plus⢠- LS-B3506 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (clone 3C8) - LS-C198328 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (C-Terminus, clone EP2693Y) - LS-C105350 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (N-Terminus) - LS-C31818 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody - LS-C137506 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (clone AP25H01) - LS-C342296 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (Ala436) - LS-C177129 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (aa401-450) - LS-C119183 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (Internal, clone EP2692Y) - LS-C105355 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (aa387-436) - LS-C200130 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (aa270-281) IHC-plus⢠- LS-B2757 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody (aa123-144) - LS-C344189 from LifeSpan Bioscience
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Anti-TFAP2C / AP2 Gamma Antibody - LS-C76481 from LifeSpan Bioscience
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