Gene Symbol | TFAP2C |
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Entrez Gene | 7022 |
Alt Symbol | AP2-GAMMA, ERF1, TFAP2G, hAP-2g |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
Other Description | activating enhancer-binding protein 2 gamma|estrogen receptor factor 1|transcription factor AP-2 gamma|transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma)|transcription factor ERF-1 |
Swissprots | O00685 Q9P1X2 Q86V30 B4DWK3 O00730 Q8IVB6 Q92754 |
Accessions | AAN37906 BAC11805 CAC86997 EAW75532 Q92754 AK301572 BAG63065 AK314272 BAG36933 BC035664 AAH35664 BC051829 AAH51829 U85658 AAC51305 X95693 CAA64989 NM_003222 NP_003213 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. {ECO:0000269|PubMed:11694877, ECO:0000269|PubMed:24413532}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:24413532}. |
AP2 gamma peptide (439-450) - ab45698 from Abcam
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Human AP2 gamma full length protein - ab132197 from Abcam
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Human AP2 gamma protein fragment - ab152738 from Abcam
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TFAP2C / AP2 Gamma Antibody Blocking Peptide - LS-E14598 from LifeSpan Bioscience
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TFAP2C / AP2 Gamma Antibody Blocking Peptide - LS-E25832 from LifeSpan Bioscience
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TFAP2C / AP2 Gamma Antibody Blocking Peptide - LS-E11812 from LifeSpan Bioscience
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Recombinant Human AP-2 gamma Protein - H00007022-Q01 from Novus Biologicals
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Recombinant Human AP-2 gamma Protein - H00007022-P01 from Novus Biologicals
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AP2 gamma blocking peptide - GTX89567-PEP from GeneTex
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Human TFAP2C protein (His Tag) - orb139724 from Biorbyt
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TFAP2C Blocking Peptide - 33R-8687 from Fitzgerald
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AP2 gamma Peptide - AC21-0664-P from Abcore
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AP2-gamma / TFAP2C - H00007022-P01-10 from Acris Antibodies
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AP2-gamma / TFAP2C - H00007022-P01-25 from Acris Antibodies
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AP2-gamma / TFAP2C - H00007022-Q01-10 from Acris Antibodies
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AP2-gamma / TFAP2C - H00007022-Q01-25 from Acris Antibodies
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AP-2 gamma Peptide - 45-259P from ProSci
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TFAP2C fusion protein - ag5648 from Proteintech Group
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TFAP2C fusion protein - Ag6004 from Proteintech Group
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Recombinant Human TFAP2C, His tagged - TFAP2C-7347H from Creative Biomart
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Human TFAP2C / AP2-GAMMA Protein (His Tag) - 13115-H07E-100 from Sino Biological
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AP2 gamma Blocking Peptide - CBP3335 from Cohesion Biosciences
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AP-2γ (A436) Peptide - BS2667P from Bioworld Technology
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Recombinant Human Transcription factor AP-2 gamma(TFAP2C) - CSB-YP842150HU CSB-EP842150HU CSB-BP842150HU CSB-MP842150HU from Cusabio
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TFAP2C Peptide - abx164824 from Abbexa
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