ISL1

Gene Symbol ISL1
Entrez Gene 3670
Alt Symbol ISLET1, Isl-1
Species Human
Gene Type protein-coding
Description ISL LIM homeobox 1
Other Description ISL1 transcription factor, LIM/homeodomain|insulin gene enhancer protein ISL-1|islet-1
Swissprots P61371
Accessions EAW54861 P61371 AK290742 BAF83431 BC017027 BC031213 AAH31213 BM680522 DQ891558 ABM82484 DQ894746 ABM85672 EU176619 ABW03420 S70721 AAD14064 U07559 AAA81946 XM_011543380 XP_011541682 NM_002202 NP_002193
Function Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.
Tissue Specificity Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Top Pathways Signaling pathways regulating pluripotency of stem cells

Human Islet 1 full length protein - ab134882 from Abcam

Category Protein
Source E. coli
Species Human

Human Islet 1 peptide - ab21996 from Abcam

Category Peptide
Dorsal root ganglion explants were dissected from 16 day-old rat embryos and cultured for 6 hours in vitro with Neurobasal Medium containing B27 supplement. Nuclei stained positive for anti-Islet 1 antibody ab20670 at 2µg/ml. As would be expected, not all cells in this preparation were Islet 1-positive. Pre-incubation of ab20670 with the immunizing peptide ab21996 resulted in complete blocking of the antibody. Green = ab20670 Blue = To-pro-3 nuclear stain The level of magnification is different in each image.

Human Islet 1 protein fragment - ab98303 from Abcam

Category Protein
Source E. coli
Species Human
5µg of ab98303 resolved by SDS-PAGE and stained with Coomassie dye.

ISLET-1 / ISL1 Antibody Blocking Peptide - LS-E4112 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ISLET-1 / ISL1 Antibody Blocking Peptide - LS-E11310 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Islet-1 Protein - H00003670-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Islet-1 Recombinant Protein - H00003670-P01 from Novus Biologicals

Category Protein

ISL1-Antibody-Center-Blocking-Peptide - BP16352c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Islet-1 / ISL1 - H00003670-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

Islet-1 / ISL1 - H00003670-P01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

Islet-1 / ISL1 - H00003670-P01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Species Human

Islet-1 / ISL1 - H00003670-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Islet-1 / ISL1 - H00003670-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Islet 1 fusion protein - ag4002 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Islet 1 fusion protein - ag8088 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human ISL1 - ISL1-28841TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human ISL1 - ISL1-129H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant ISL LIM Homeobox Protein 1 (ISL1) - RPJ985Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant ISL LIM Homeobox Protein 1 (ISL1) - RPJ985Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Insulin gene enhancer protein ISL-1(ISL1) - CSB-YP011846HU CSB-EP011846HU CSB-BP011846HU CSB-MP011846HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Islet-1 Recombinant Protein Antigen - NBP2-33831PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ISL1 Peptide, Human - M34GP07765H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

ISL1 Antibody - SH-A13007 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Species Human, Mouse, Rat

Insulin gene enhancer protein ISL-1 (ISL1), Recombinant Protein - MBS959011 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,760.00, $1,760.00, $2,225.00, $2,225.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

ISL LIM Homeobox Protein 1, Recombinant Protein - MBS2033471 from MyBioSource

Category Protein
Prices $185.00, $380.00, $585.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Human
Search more