ISL1

Gene Symbol ISL1
Entrez Gene 3670
Alt Symbol ISLET1, Isl-1
Species Human
Gene Type protein-coding
Description ISL LIM homeobox 1
Other Description ISL1 transcription factor, LIM/homeodomain|insulin gene enhancer protein ISL-1|islet-1
Swissprots P61371
Accessions EAW54861 P61371 AK290742 BAF83431 BC017027 BC031213 AAH31213 BM680522 DQ891558 ABM82484 DQ894746 ABM85672 EU176619 ABW03420 S70721 AAD14064 U07559 AAA81946 XM_011543380 XP_011541682 NM_002202 NP_002193
Function Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.
Tissue Specificity Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Top Pathways Signaling pathways regulating pluripotency of stem cells

Islet-1 CRISPR/Cas9 KO Plasmid (h) - sc-401733 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 HDR Plasmid (h) - sc-401733-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 Double Nickase Plasmid (h) - sc-401733-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 Double Nickase Plasmid (h2) - sc-401733-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 CRISPR Activation Plasmid (h) - sc-401733-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 CRISPR Activation Plasmid (h2) - sc-401733-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 Lentiviral Activation Particles (h) - sc-401733-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 Lentiviral Activation Particles (h2) - sc-401733-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Islet-1 siRNA (h) - sc-37121 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Islet-1 shRNA Plasmid (h) - sc-37121-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Islet-1 shRNA (h) Lentiviral Particles - sc-37121-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Islet-1 RNAi - H00003670-R01V from Novus Biologicals

Category siRNA
Prices $629.00
Sizes 20 nmol
Species Reactivities Human
Western blot analysis of ISL1 over-expressed 293 cell line, cotransfected with ISL1 Validated Chimera RNAi or non-transfected control. Blot probed with H00003670-M01. GAPDH (36.1 kDa) used as loading control.

Islet-1 RNAi - H00003670-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10789 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10789 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07972 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07972

ISL1 siRNA (Human) - CRH2461 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ISL1 - MBS8219560 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ISL1 (NM_002202.2) - SHH320941 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ISL1(NM_002202.2) - SHL174450 from Creative biogene

Category siRNA
Species Reactivities Human

Human ISL1 siRNA - orb262963 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ISL1 shRNA Plasmid (Human) - CHH2461 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ISL1 miRNA 3'UTR clone - MiUTR1H-05010 from Creative biogene

Species Reactivities Human
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