ULBP3

Gene Symbol ULBP3
Entrez Gene 79465
Alt Symbol RAET1N
Species Human
Gene Type protein-coding
Description UL16 binding protein 3
Other Description ALCAN-gamma|N2DL-3|NKG2D ligand 3|NKG2DL3|UL16-binding protein 3|retinoic acid early transcript 1N
Swissprots Q5VY82 Q9BZM4 Q8IZX5 Q8TE75
Accessions EAW47772 Q9BZM4 AB052908 BAB61050 AF304379 AAK13083 AF346596 AAN40839 AK297815 BAG60153 AK302076 BAG63465 AK315275 BAG37687 AY027538 AAK13049 BC098127 AAH98127 XM_005267137 XP_005267194 NM_024518 NP_078794
Function Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for KLRK1/NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. {ECO:0000269|PubMed:11777960}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Top Pathways Natural killer cell mediated cytotoxicity

ULBP3 (2F9) - sc-53132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ULBP3 (2F9): sc-53132. Indirect FCM analysis of C1R mock (black line histogram) and C1R-ULBP3 transfectants (solid histogram) stained with ULBP3 (2F9) followed by PE-conjugated goat anti-mouse IgG. Kindly provided by Nobuyoshi Hanaoka and Veronika Groh at Fred Hutchinson Cancer Research Center.

ULBP3 (D-1) - sc-390844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ULBP3 (D-1): sc-390844. Western blot analysis of ULBP3 expression in HeLa (A) and Hep G2 (B) whole cell lysates.

ULBP3 (H-45) - sc-33566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ULBP3 (L-20) - sc-20574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ULBP3 (L-20): sc-20574. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ULBP3 (YY42) - sc-80420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-ULBP3 antibody [MM0594-6E12] - ab89931 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0594-6E12
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling ULBP3 with ab89931. Tissue was treated with 15µg/ml Protenase for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

Anti-ULBP3 Antibody (PE) - LS-C144249 from LifeSpan Bioscience

Prices $530.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

ULBP-3 Antibody (166510) - MAB1517 from Novus Biologicals

Prices $99.00, $269.00, $699.00
Sizes 25 µg, 100 µg, 500 µg
Host Mouse
Clonality Monoclonal
Clone 166510

ULBP-3 Antibody - AF1517 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

ULBP-3 Antibody - NBP2-31866 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ULBP3 Antibody [NBP2-31866] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.

ULBP-3 Antibody (MM0594-6E12) - NBP2-11988 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0594-6E12
Immunohistochemistry-Paraffin: ULBP-3 Antibody (MM0594-6E12) [NBP2-11988] - 4% PFA fixed and parffine embedded human placental tissue section (4um) is subjected to IHC staining. Tissue was treated with 15ug/ml Protenase for antige retrieval before IHC is applied.

ULBP-3 Antibody (166510) [Phycoerythrin] - FAB1517P from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 166510
Human monocyte-derived dendritic cells were stained with Mouse Anti-Human ULBP-3 PE-conjugated Monoclonal Antibody (Catalog # FAB1517P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

ULBP-3 Antibody [Biotin] - BAF1517 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

ULBP-3 Antibody (166510) [Allophycocyanin] - FAB1517A from Novus Biologicals

Prices $369.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 166510
BaF3 mouse pro-B cell line transfected with human ULBP-3 was stained with Mouse Anti-Human ULBP-3 APC-conjugated Monoclonal Antibody (Catalog # FAB1517A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Rabbit Anti-ULBP3 Polyclonal Antibody - bs-2730R from Bioss

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-ULBP3/N2DL3 Polyclonal Antibody, Unconjugated (bs-2730R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-ULBP3 antibody produced in rabbit - HPA063007 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ULBP3: <B>Cat. No. HPA063007</B>: Immunohistochemical staining of Human spleen shows strong cytoplasmic positivity in cells in red pulp.

Human ULBP-3 PE-conjugated Antibody - FAB1517P from R&D Systems

Prices $329.00
Sizes 100 tests
Host Mouse
Clone 166510
Detection of ULBP‑3 in Human monocyte-derived dendritic cells by Flow Cytometry. Human monocyte-derived dendritic cells were stained with Mouse Anti-Human ULBP-3 PE-conjugated Monoclonal Antibody (Catalog # FAB1517P, filled histogram) or isotype control antibody (Catalog # IC003P , open histogram). View our protocol for Staining Membrane-associated Proteins .

Human ULBP-3 MAb (Clone 166510), Mouse IgG2A - MAB1517-100 from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 166510

Human ULBP-3 MAb (Clone 166510), Mouse IgG2A - MAB1517-500 from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 166510

Human ULBP-3 MAb (Clone 166510), Mouse IgG2A - MAB1517-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 166510

Human ULBP-3 Antibody - AF1517 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat

Human ULBP-3 Affinity Purified Polyclonal Ab, Goat IgG - AF1517-SP from R&D Systems

Host Goat
Clonality Polyclonal

Human ULBP-3 APC-conjugated Antibody - FAB1517A from R&D Systems

Prices $369.00
Sizes 100 tests
Host Mouse
Clone 166510
Detection of ULBP-3 in BaF3 Mouse Cell Line Transfected with Human ULBP-3 by Flow Cytometry. BaF3 mouse pro-B cell line transfected with human ULBP-3 was stained with Mouse Anti-Human ULBP-3 APC-conjugated Monoclonal Antibody (Catalog # FAB1517A, filled histogram) or isotype control antibody (Catalog # IC003A , open histogram). View our protocol for Staining Membrane-associated Proteins .

Human ULBP-3 Antibody - MAB15171 from R&D Systems

Prices $99.00, $339.00
Sizes 25 µg, 500 µg
Host Mouse
Clone 166514

Human ULBP-3 MAb (Clone 166514), Mouse IgG2A - MAB15171-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 166514
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