ULBP3

Gene Symbol ULBP3
Entrez Gene 79465
Alt Symbol RAET1N
Species Human
Gene Type protein-coding
Description UL16 binding protein 3
Other Description ALCAN-gamma|N2DL-3|NKG2D ligand 3|NKG2DL3|UL16-binding protein 3|retinoic acid early transcript 1N
Swissprots Q5VY82 Q9BZM4 Q8IZX5 Q8TE75
Accessions EAW47772 Q9BZM4 AB052908 BAB61050 AF304379 AAK13083 AF346596 AAN40839 AK297815 BAG60153 AK302076 BAG63465 AK315275 BAG37687 AY027538 AAK13049 BC098127 AAH98127 XM_005267137 XP_005267194 NM_024518 NP_078794
Function Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for KLRK1/NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. {ECO:0000269|PubMed:11777960}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Top Pathways Natural killer cell mediated cytotoxicity

ULBP3 CRISPR/Cas9 KO Plasmid (h) - sc-403608 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 HDR Plasmid (h) - sc-403608-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 Double Nickase Plasmid (h) - sc-403608-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 Double Nickase Plasmid (h2) - sc-403608-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 CRISPR Activation Plasmid (h) - sc-403608-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 CRISPR Activation Plasmid (h2) - sc-403608-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 Lentiviral Activation Particles (h) - sc-403608-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 Lentiviral Activation Particles (h2) - sc-403608-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ULBP3 siRNA (h) - sc-43006 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ULBP3 shRNA Plasmid (h) - sc-43006-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ULBP3 shRNA (h) Lentiviral Particles - sc-43006-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ULBP-3 RNAi - H00079465-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU021341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22485 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22485 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ULBP3 siRNA (Human) - CRJ2390 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ULBP3 - MBS8240152 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ULBP3 (NM_024518.1) - SHH440368 from Creative biogene

Category siRNA
Species Reactivities Human

Human ULBP3 siRNA - orb272891 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ULBP3 shRNA Plasmid (Human) - CHJ2390 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ULBP3 miRNA 3'UTR clone - MiUTR1H-11003 from Creative biogene

Species Reactivities Human
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