ULBP3

Gene Symbol	ULBP3
Entrez Gene	79465
Alt Symbol	RAET1N
Species	Human
Gene Type	protein-coding
Description	UL16 binding protein 3
Other Description	ALCAN-gamma|N2DL-3|NKG2D ligand 3|NKG2DL3|UL16-binding protein 3|retinoic acid early transcript 1N
Swissprots	Q5VY82 Q9BZM4 Q8IZX5 Q8TE75
Accessions	EAW47772 Q9BZM4 AB052908 BAB61050 AF304379 AAK13083 AF346596 AAN40839 AK297815 BAG60153 AK302076 BAG63465 AK315275 BAG37687 AY027538 AAK13049 BC098127 AAH98127 XM_005267137 XP_005267194 NM_024518 NP_078794
Function	Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for KLRK1/NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. {ECO:0000269|PubMed:11777960}.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Top Pathways	Natural killer cell mediated cytotoxicity

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ULBP3-Antibody-C-term-Blocking-Peptide - BP16963b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ULBP-3 Fc Chimera, CF - 1517-UL-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human UL16 Binding Protein 3, His-tagged - ULBP3-5186H from Creative Biomart Category Protein Source Human

Recombinant Human ULBP3, Fc Chimera - ULBP3-754H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human NKG2D ligand 3(ULBP3) - CSB-YP883648HU CSB-EP883648HU CSB-BP883648HU CSB-MP883648HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human ULBP-3 Fc Chimera Protein, CF - 1517-UL from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human ULBP-3 (Gly27 - Pro216 & His32 - Pro216) Accession # NP_078794 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Human

Human ULBP3 protein - orb260153 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

ULBP-3 Recombinant Protein Antigen - NBP2-31866PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ULBP3 Peptide, Human - M34GP17075H from Creative Peptides Category Peptide Source Synthetic. Species Human

NKG2D ligand 3 (ULBP3), Recombinant Protein - MBS1370146 from MyBioSource Category Protein Prices $935.00, $935.00, $1,160.00, $1,160.00, $1,400.00, $1,400.00, $1,855.00, $1,855.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human ULBP-3 Fc Chimera Protein, CF - 1517-UL from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

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