COTL1

Gene Symbol	COTL1
Entrez Gene	23406
Alt Symbol	CLP
Species	Human
Gene Type	protein-coding
Description	coactosin-like F-actin binding protein 1
Other Description	coactosin-like 1|coactosin-like protein
Swissprots	D3DUL9 Q14019 B2RDU3 Q86XM5
Accessions	EAW95475 EAW95476 EAW95477 Q14019 AK026033 AK093712 AK125645 AK127352 AK315675 BAG38040 BC010039 AAH10039 BC010884 AAH10884 BC016702 AAH16702 BC020445 BC042970 AAH42970 BC053682 AAH53682 BT006968 AAP35614 BX395081 DA968872 EU832743 ACE87075 JF432552 ADZ15769 L08436 L54057 AAA88022 NM_021149 NP_066972
Function	Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. {ECO:0000269|PubMed:11583571, ECO:0000269|PubMed:19807693}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus membrane; Peripheral membrane protein.
Tissue Specificity	Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. {ECO:0000269|PubMed:11583571}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human COTL1 full length protein - ab116193 from Abcam Category Protein Source E. coli Species Human

CLP / COTL1 Antibody Blocking Peptide - LS-E9797 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Coactosin-like Protein 1/CotL1 Partial Recombinant Protein - H00023406-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Coactosin-like Protein 1/CotL1 Recombinant Protein - H00023406-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human Coactosin-like Protein 1/CotL1 Protein - NBP1-50942 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

COTL1-Antibody-C-term-Blocking-Peptide - BP8819b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

COTL1 Protein (OPPA00048) - OPPA00048 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human COTL1 protein - orb244819 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human COTL1 protein - orb168148 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Coactosin-Like 1 Blocking Peptide - 33R-5779 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

COTL1 protein (His tag) - 80R-1617 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Coactosin-like protein (1-142, His-tag) - AR09798PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Coactosin-like protein (1-142, His-tag) - AR09798PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Coactosin-like protein - H00023406-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Coactosin-like protein - H00023406-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

COTL1 - H00023406-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Coactosin-Like 1, Human Recombinant - 228-12784-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Coactosin-Like 1 Human - 228-12784-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Coactosin-Like 1 Human - 228-12784-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

COTL1, 1-142aa, Human, His tag, E.coli - 01-P0858 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

COTL1 fusion protein - Ag1230 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

COTL1 Human - PRPS-071 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Coactosin-Like 1 Protein - BP001538-PRO-064 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

COTL1, 1-142aa, Recombinant Protein - GWB-P1180J from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

COTL1 Human Protein - GWB-BSP439 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

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