Gene Symbol | COTL1 |
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Entrez Gene | 23406 |
Alt Symbol | CLP |
Species | Human |
Gene Type | protein-coding |
Description | coactosin-like F-actin binding protein 1 |
Other Description | coactosin-like 1|coactosin-like protein |
Swissprots | D3DUL9 Q14019 B2RDU3 Q86XM5 |
Accessions | EAW95475 EAW95476 EAW95477 Q14019 AK026033 AK093712 AK125645 AK127352 AK315675 BAG38040 BC010039 AAH10039 BC010884 AAH10884 BC016702 AAH16702 BC020445 BC042970 AAH42970 BC053682 AAH53682 BT006968 AAP35614 BX395081 DA968872 EU832743 ACE87075 JF432552 ADZ15769 L08436 L54057 AAA88022 NM_021149 NP_066972 |
Function | Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. {ECO:0000269|PubMed:11583571, ECO:0000269|PubMed:19807693}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus membrane; Peripheral membrane protein. |
Tissue Specificity | Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. {ECO:0000269|PubMed:11583571}. |
COTL1 (F-12) - sc-160246 from Santa Cruz Biotechnology
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COTL1 (T-12) - sc-160247 from Santa Cruz Biotechnology
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Anti-COTL1 antibody - ab93427 from Abcam
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Anti-COTL1 antibody [AT1D6] - ab187608 from Abcam
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Anti-CLP / COTL1 Antibody (aa65-79) - LS-C190693 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, AP) - LS-C206501 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, APC) - LS-C206502 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, Biotin) - LS-C206503 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (N-Terminus) - LS-C107904 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, FITC) - LS-C206504 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, Azide-free, HRP) - LS-C207960 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (Biotin) - LS-C318353 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody - LS-C318657 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (HRP) - LS-C318658 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (FITC) - LS-C318660 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142) - LS-C327107 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (clone 5C8E3) - LS-C169157 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (clone 5C8) - LS-C169468 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142) - LS-C166960 from LifeSpan Bioscience
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Anti-CLP / COTL1 Antibody (aa113-142, PE) - LS-C206506 from LifeSpan Bioscience
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Coactosin-like Protein 1/CotL1 Antibody - NBP1-54851 from Novus Biologicals
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Coactosin-like Protein 1/CotL1 Antibody - AF7865 from Novus Biologicals
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Coactosin-like Protein 1/CotL1 Antibody (5C8) - NBP2-37519 from Novus Biologicals
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Coactosin-like Protein 1/CotL1 Antibody (5C8E3) - NBP2-37517 from Novus Biologicals
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Coactosin-like Protein 1/CotL1 Antibody (1D6) - NBP2-31203 from Novus Biologicals
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