Gene Symbol | ATXN7 |
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Entrez Gene | 6314 |
Alt Symbol | ADCAII, OPCA3, SCA7 |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 7 |
Other Description | ataxin-7|spinocerebellar ataxia type 7 protein |
Swissprots | Q9Y6P8 E9PHP9 B4E207 O75329 O75328 O15265 |
Accessions | AAB87863 AAC19162 AAL79807 EAW65422 EAW65423 O15265 AA398030 AF032103 AAC19163 AF032104 AAC19164 AF032105 AAC39765 AJ000517 CAA04154 AK125125 AK304062 BAG64969 AK310745 AL134602 BC166666 AAI66666 BI494079 BP220889 NM_000333 NP_000324 NM_001128149 NP_001121621 NM_001177387 NP_001170858 |
Function | Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. {ECO:0000269|PubMed:22100762}. |
Subcellular Location | Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm. |
Tissue Specificity | Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine. |
Ataxin-7 (C-21) - sc-21112 from Santa Cruz Biotechnology
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Ataxin-7 (N-17) - sc-21110 from Santa Cruz Biotechnology
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Anti-Ataxin 7 antibody - ab11434 from Abcam
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Anti-Ataxin 7 antibody - ab90907 from Abcam
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Anti-Ataxin 7 antibody - ab85079 from Abcam
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Anti-Ataxin 7 antibody - ab95013 from Abcam
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa842-892) - LS-C286132 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody - LS-C126934 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, APC) - LS-C252097 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, FITC) - LS-C252099 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, Biotin) - LS-C252098 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, AP) - LS-C252096 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, Azide-free, HRP) - LS-C252100 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381, PE) - LS-C252101 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381) - LS-C329240 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (N-Terminus) - LS-C170184 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa359-408) - LS-C109782 from LifeSpan Bioscience
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Anti-ATXN7 / SCA7 / Ataxin-7 Antibody (aa353-381) - LS-C156685 from LifeSpan Bioscience
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Ataxin 7 Antibody - NBP1-90236 from Novus Biologicals
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Ataxin 7 Antibody - NBP1-42657 from Novus Biologicals
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Ataxin 7 Polyclonal Antibody - bs-11318R from Bioss
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Ataxin 7 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11318R-A350 from Bioss
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Ataxin 7 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11318R-A488 from Bioss
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Ataxin 7 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11318R-A555 from Bioss
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Ataxin 7 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11318R-A647 from Bioss
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