Gene Symbol | ATXN7 |
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Entrez Gene | 6314 |
Alt Symbol | ADCAII, OPCA3, SCA7 |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 7 |
Other Description | ataxin-7|spinocerebellar ataxia type 7 protein |
Swissprots | Q9Y6P8 E9PHP9 B4E207 O75329 O75328 O15265 |
Accessions | AAB87863 AAC19162 AAL79807 EAW65422 EAW65423 O15265 AA398030 AF032103 AAC19163 AF032104 AAC19164 AF032105 AAC39765 AJ000517 CAA04154 AK125125 AK304062 BAG64969 AK310745 AL134602 BC166666 AAI66666 BI494079 BP220889 NM_000333 NP_000324 NM_001128149 NP_001121621 NM_001177387 NP_001170858 |
Function | Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. {ECO:0000269|PubMed:22100762}. |
Subcellular Location | Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm. |
Tissue Specificity | Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine. |
Human Ataxin 7 peptide - ab39761 from Abcam
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ATXN7 / SCA7 / Ataxin-7 Antibody Blocking Peptide - LS-E4578 from LifeSpan Bioscience
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ATXN7 / SCA7 / Ataxin-7 Antibody Blocking Peptide - LS-E11773 from LifeSpan Bioscience
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ATXN7 / SCA7 / Ataxin-7 Antibody Blocking Peptide - LS-E13621 from LifeSpan Bioscience
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ATXN7-Antibody-Center-Blocking-Peptide - BP16926c from Abgent, a WuXi AppTec company
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ATXN7 Blocking Peptide - 33R-9268 from Fitzgerald
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Ataxin 7 Blocking Peptide - abx161290 from Abbexa
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Ataxin-7 control peptide - SP5266CP from Acris Antibodies
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Recombinant Human ATXN7, His-tagged - ATXN7-3690H from Creative Biomart
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Ataxin 7 Blocking Peptide - CBP3789 from Cohesion Biosciences
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Recombinant Human Ataxin-7(ATXN7) ,partial - CSB-YP002445HU CSB-EP002445HU CSB-BP002445HU CSB-MP002445HU from Cusabio
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Ataxin-7(ATXN7) ,partial, Recombinant Protein - MBS1219994 from MyBioSource
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Ataxin 7 Protein - NBP1-90236PEP from Novus Biologicals
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ATXN7 Peptide, Human - M34GP01223H from Creative Peptides
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Ataxin 7 peptide - orb234664 from Biorbyt
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ATXN7 fusion protein - Ag26779 from Proteintech Group
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ATXN7 fusion protein - Ag26806 from Proteintech Group
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