ATXN7

Gene Symbol ATXN7
Entrez Gene 6314
Alt Symbol ADCAII, OPCA3, SCA7
Species Human
Gene Type protein-coding
Description ataxin 7
Other Description ataxin-7|spinocerebellar ataxia type 7 protein
Swissprots Q9Y6P8 E9PHP9 B4E207 O75329 O75328 O15265
Accessions AAB87863 AAC19162 AAL79807 EAW65422 EAW65423 O15265 AA398030 AF032103 AAC19163 AF032104 AAC19164 AF032105 AAC39765 AJ000517 CAA04154 AK125125 AK304062 BAG64969 AK310745 AL134602 BC166666 AAI66666 BI494079 BP220889 NM_000333 NP_000324 NM_001128149 NP_001121621 NM_001177387 NP_001170858
Function Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. {ECO:0000269|PubMed:22100762}.
Subcellular Location Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.
Tissue Specificity Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine.

Ataxin-7 CRISPR/Cas9 KO Plasmid (h) - sc-408149 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 HDR Plasmid (h) - sc-408149-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 Double Nickase Plasmid (h) - sc-408149-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 Double Nickase Plasmid (h2) - sc-408149-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 CRISPR Activation Plasmid (h) - sc-408149-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 CRISPR Activation Plasmid (h2) - sc-408149-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 Lentiviral Activation Particles (h) - sc-408149-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 Lentiviral Activation Particles (h2) - sc-408149-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-7 siRNA (h) - sc-40360 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-7 shRNA Plasmid (h) - sc-40360-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-7 shRNA (h) Lentiviral Particles - sc-40360-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin 7 RNAi - H00006314-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU098901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3764 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3764 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08773 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08773

ATXN7 siRNA (Human) - CRH4254 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN7 - MBS8202047 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATXN7 (NM_000333.3) - SHH243598 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATXN7 siRNA - orb264756 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN7 shRNA Plasmid (Human) - CHH4254 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATXN7 miRNA 3'UTR clone - MiUTR4H-TG00666 from Creative biogene

Species Reactivities Human
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