| Gene Symbol | ATXN7 |
|---|---|
| Entrez Gene | 6314 |
| Alt Symbol | ADCAII, OPCA3, SCA7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ataxin 7 |
| Other Description | ataxin-7|spinocerebellar ataxia type 7 protein |
| Swissprots | Q9Y6P8 E9PHP9 B4E207 O75329 O75328 O15265 |
| Accessions | AAB87863 AAC19162 AAL79807 EAW65422 EAW65423 O15265 AA398030 AF032103 AAC19163 AF032104 AAC19164 AF032105 AAC39765 AJ000517 CAA04154 AK125125 AK304062 BAG64969 AK310745 AL134602 BC166666 AAI66666 BI494079 BP220889 NM_000333 NP_000324 NM_001128149 NP_001121621 NM_001177387 NP_001170858 |
| Function | Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. {ECO:0000269|PubMed:22100762}. |
| Subcellular Location | Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm. |
| Tissue Specificity | Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine. |
Ataxin-7 (ATXN7), Human, ELISA Kit - E01A1770 from ARP American Research Products
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ataxin 7, ELISA Kit - MBS9321816 from MyBioSource
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Ataxin 7 (ATXN7), ELISA Kit - MBS7238423 from MyBioSource
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Ataxin 7 (ATXN7), ELISA Kit - MBS9312106 from MyBioSource
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Human ATXN7 ELISA Kit - E003915 from Biobool
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