Gene Symbol | RGS17 |
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Entrez Gene | 26575 |
Alt Symbol | RGS-17, RGSZ2, hRGS17 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 17 |
Other Description | - |
Swissprots | Q8TD61 Q5TF49 Q9UJS8 Q9UGC6 |
Accessions | CAK32368 EAW47711 Q9UGC6 AA902430 AF202257 AAF08978 AF493938 AAM12652 BC013117 AAH13117 BT006997 AAP35643 CK902282 XM_011535752 XP_011534054 XM_011535753 XP_011534055 XM_011535754 XP_011534056 NM_012419 NP_036551 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G- protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation (By similarity). {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in the cerebellum. Also expressed in the cortex and medulla. Weakly expressed in a number of peripheral tissues notably spleen, lung and leukocytes. {ECO:0000269|PubMed:15096504}. |
RGS17 (H-40) - sc-99133 from Santa Cruz Biotechnology
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RGS17 (Q-20) - sc-48285 from Santa Cruz Biotechnology
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RGS17 (W-15) - sc-48286 from Santa Cruz Biotechnology
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Anti-RGS17 / RGSZ2 antibody - ab96675 from Abcam
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Anti-RGS17 / RGSZ2 antibody - ab150814 from Abcam
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Anti-RGS17 / RGSZ2 Antibody (aa148-210) - LS-C185811 from LifeSpan Bioscience
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Anti-RGS17 / RGSZ2 Antibody (aa41-100) - LS-C91020 from LifeSpan Bioscience
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Anti-RGS17 / RGSZ2 Antibody (aa198-210) - LS-C55388 from LifeSpan Bioscience
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Anti-RGS17 / RGSZ2 Antibody - LS-C341027 from LifeSpan Bioscience
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Anti-RGS17 / RGSZ2 Antibody (aa160-209) - LS-C205652 from LifeSpan Bioscience
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RGS17 Antibody - NBP1-33694 from Novus Biologicals
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RGS17 Antibody - NB120-14260 from Novus Biologicals
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RGS17 Antibody - NBP1-80839 from Novus Biologicals
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RGS17 Antibody - NBP2-20149 from Novus Biologicals
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RGS17 Antibody - H00026575-A01 from Novus Biologicals
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RGS17 Antibody (2H4) - H00026575-M01A from Novus Biologicals
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Anti-RGS17 antibody produced in chicken - GW22898 from Sigma-Aldrich
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Anti-RGS17 (C-terminal) antibody produced in rabbit - SAB2702011 from Sigma-Aldrich
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Monoclonal Anti-RGS17 antibody produced in mouse - SAB1403191 from Sigma-Aldrich
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Anti-RGS17 antibody produced in rabbit - HPA022276 from Sigma-Aldrich
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RGS17 Antibody - C-terminal region (ARP34049_P050) - ARP34049_P050 from Aviva Systems Biology
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RGS17--RGSZ2-Antibody-C-Term - AF2409a from Abgent, a WuXi AppTec company
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Goat Anti-RGS17 / RGSZ2 Antibody (OAEB00231) - OAEB00231 from Aviva Systems Biology
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RGS17 antibody (OAGA00507) - OAGA00507 from Aviva Systems Biology
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RGS17 antibody - orb73627 from Biorbyt
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