UBASH3A

Gene Symbol UBASH3A
Entrez Gene 53347
Alt Symbol CLIP4, STS-2, TULA, TULA-1
Species Human
Gene Type protein-coding
Description ubiquitin associated and SH3 domain containing A
Other Description T-cell ubiquitin ligand 1|T-cell ubiquitin ligand protein|cbl-interacting protein 4|suppressor of T-cell receptor signaling 2|ubiquitin-associated and SH3 domain-containing protein A
Swissprots Q6ISK3 G5E9E4 Q6ISI6 Q6ISS9 P57075 Q6HA35 Q6HA34
Accessions CAH05300 EAX09560 EAX09561 EAX09562 EAX09563 P57075 AA707211 AF520809 AAP80731 AF521702 AAP80738 AJ277750 CAB91543 AK301279 BAG62839 AK308151 AK313367 BC028138 AAH28138 BC069357 AAH69357 BC069483 AAH69483 BC069511 AAH69511 BC069577 DA926085 XM_006724013 XP_006724076 XM_011529605 XP_011527907 XM_011529606 XP_011527908 XM_011529607 XP_011527909 XM_011529608 XP_011527910 XM_011529609 XP_011527911 XM_011529610 XP_011527912 XR_244316 XR_937510 NM_001001895 NP_001001895 NM_001243467 NP_001230396 NM_018961 NP_061834
Function Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. {ECO:0000269|PubMed:15159412, ECO:0000269|PubMed:17382318, ECO:0000269|PubMed:18189269}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Highest expression of UBASH3A in tissues belonging to the immune system, including spleen, peripheral blood leukocytes, thymus and bone marrow. {ECO:0000269|PubMed:11281453, ECO:0000269|PubMed:15107835}.

TULA (K-18) - sc-83340 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A antibody - ab115033 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-UBASH3A antibody (ab115033) at 1 µg/ml + Human spleen lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-UBASH3A antibody - ab197168 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human fetal spleen tissue labeling UBASH3A with ab197168 at 1/100 dilution.

Anti-UBASH3A antibody - ab169581 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-UBASH3A antibody (ab169581) at 1/500 dilutionLane 1 : UBASH3A-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-UBASH3A antibody - ab138957 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UBASH3A antibody (ab138957) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

Anti-UBASH3A antibody - ab59122 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ab59122 (2.5 µg/ml) staining UBASH3A in human spleen by IHC-P.  Steamed antigen retrieval with citrate buffer pH 6, AP-staining.  The image shows cytoplasm staining of T-cells eccentrically gathered around an artery.

Anti-UBASH3A / CLIP4 Antibody (aa312-340, AP) - LS-C272855 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa312-340, Biotin) - LS-C272857 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa312-340, APC) - LS-C272856 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody - LS-C155452 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: THP-1 10% SDS PAGE UBASH3A antibody diluted at 1:2000

Anti-UBASH3A / CLIP4 Antibody (aa312-340, FITC) - LS-C272858 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa312-340, Azide-free, HRP) - LS-C272859 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa312-340, PE) - LS-C272860 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa311-360) - LS-C291405 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa312-340) - LS-C330273 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa356-401) - LS-C313988 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UBASH3A / CLIP4 Antibody (aa434-483) - LS-C80770 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-UBASH3A / CLIP4 Antibody (aa313-340) - LS-C157308 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UBASH3A Antibody western blot of mouse heart tissue lysates (35 ug/lane). The UBASH3A antibody detected the UBASH3A protein (arrow).

Anti-UBASH3A / CLIP4 Antibody (aa417-430) IHC-plus™ - LS-B1765 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-UBASH3A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1765 concentration 5 ug/ml.

Anti-UBASH3A / CLIP4 Antibody (aa470-482) IHC-plus™ - LS-B8359 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-UBASH3A antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8359 dilution 3.75 ug/ml.

TULA/STS-2 Antibody - NBP2-20763 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TULA/STS-2 Antibody - H00053347-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: TULA/STS-2 Antibody [H00053347-B01] - analysis of UBASH3A expression in transfected 293T cell line by UBASH3A MaxPab polyclonal antibody (B01). Lane1: UBASH3A transfected lysate (50.40 KDa). Lane2: Non-transfected lysate.

TULA/STS-2 Antibody - NB100-57842 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: TULA/STS-2 Antibody [NB100-57842] - IHC analysis of TULA/STS-2 in paraffin-embedded Human Spleen using NB100-57842 at 2.5ug/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

TULA/STS-2 Antibody - NBP2-20762 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TULA/STS-2 Antibody [NBP2-20762] - Sample (30 ug of whole cell lysate) A: THP-1 10% SDS PAGE gel, diluted at 1:2000.

TULA/STS-2 Antibody - H00053347-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TULA/STS-2 Antibody [H00053347-D01P] - Analysis of UBASH3A expression in transfected 293T cell line by UBASH3A polyclonal antibody.Lane 1: UBASH3A transfected lysate(50.40 KDa).Lane 2: Non-transfected lysate.
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