UBASH3A

Gene Symbol	UBASH3A
Entrez Gene	53347
Alt Symbol	CLIP4, STS-2, TULA, TULA-1
Species	Human
Gene Type	protein-coding
Description	ubiquitin associated and SH3 domain containing A
Other Description	T-cell ubiquitin ligand 1|T-cell ubiquitin ligand protein|cbl-interacting protein 4|suppressor of T-cell receptor signaling 2|ubiquitin-associated and SH3 domain-containing protein A
Swissprots	Q6ISK3 G5E9E4 Q6ISI6 Q6ISS9 P57075 Q6HA35 Q6HA34
Accessions	CAH05300 EAX09560 EAX09561 EAX09562 EAX09563 P57075 AA707211 AF520809 AAP80731 AF521702 AAP80738 AJ277750 CAB91543 AK301279 BAG62839 AK308151 AK313367 BC028138 AAH28138 BC069357 AAH69357 BC069483 AAH69483 BC069511 AAH69511 BC069577 DA926085 XM_006724013 XP_006724076 XM_011529605 XP_011527907 XM_011529606 XP_011527908 XM_011529607 XP_011527909 XM_011529608 XP_011527910 XM_011529609 XP_011527911 XM_011529610 XP_011527912 XR_244316 XR_937510 NM_001001895 NP_001001895 NM_001243467 NP_001230396 NM_018961 NP_061834
Function	Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. {ECO:0000269|PubMed:15159412, ECO:0000269|PubMed:17382318, ECO:0000269|PubMed:18189269}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Highest expression of UBASH3A in tissues belonging to the immune system, including spleen, peripheral blood leukocytes, thymus and bone marrow. {ECO:0000269|PubMed:11281453, ECO:0000269|PubMed:15107835}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBASH3A 293T Cell Transient Overexpression Lysate(Denatured) - H00053347-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

UBASH3A overexpression lysate - LY412849 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

UBASH3A overexpression lysate - LY424264 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

UBASH3A 293 Cell Lysate - 406265 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TULA/STS-2 Overexpression Lysate (Denatured) - H00053347-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

TULA/STS-2 Overexpression Lysate (Native) - NBL1-17506 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBASH3A Over-expression Lysate Product - GWB-A9AC83 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

TULA/STS-2 Overexpression Lysate (Native) - NBP2-10728 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human UBASH3A Knockdown Stable Cell Line - CSC-DC016942 from Creative biogene Category Cell Line Species Human

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