UBASH3A

Gene Symbol UBASH3A
Entrez Gene 53347
Alt Symbol CLIP4, STS-2, TULA, TULA-1
Species Human
Gene Type protein-coding
Description ubiquitin associated and SH3 domain containing A
Other Description T-cell ubiquitin ligand 1|T-cell ubiquitin ligand protein|cbl-interacting protein 4|suppressor of T-cell receptor signaling 2|ubiquitin-associated and SH3 domain-containing protein A
Swissprots Q6ISK3 G5E9E4 Q6ISI6 Q6ISS9 P57075 Q6HA35 Q6HA34
Accessions CAH05300 EAX09560 EAX09561 EAX09562 EAX09563 P57075 AA707211 AF520809 AAP80731 AF521702 AAP80738 AJ277750 CAB91543 AK301279 BAG62839 AK308151 AK313367 BC028138 AAH28138 BC069357 AAH69357 BC069483 AAH69483 BC069511 AAH69511 BC069577 DA926085 XM_006724013 XP_006724076 XM_011529605 XP_011527907 XM_011529606 XP_011527908 XM_011529607 XP_011527909 XM_011529608 XP_011527910 XM_011529609 XP_011527911 XM_011529610 XP_011527912 XR_244316 XR_937510 NM_001001895 NP_001001895 NM_001243467 NP_001230396 NM_018961 NP_061834
Function Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. {ECO:0000269|PubMed:15159412, ECO:0000269|PubMed:17382318, ECO:0000269|PubMed:18189269}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Highest expression of UBASH3A in tissues belonging to the immune system, including spleen, peripheral blood leukocytes, thymus and bone marrow. {ECO:0000269|PubMed:11281453, ECO:0000269|PubMed:15107835}.

TULA CRISPR/Cas9 KO Plasmid (h) - sc-408889 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA HDR Plasmid (h) - sc-408889-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA Double Nickase Plasmid (h) - sc-408889-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA Double Nickase Plasmid (h2) - sc-408889-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA CRISPR Activation Plasmid (h) - sc-408889-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA CRISPR Activation Plasmid (h2) - sc-408889-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA Lentiviral Activation Particles (h) - sc-408889-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA Lentiviral Activation Particles (h2) - sc-408889-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULA siRNA (h) - sc-91418 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULA shRNA Plasmid (h) - sc-91418-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULA shRNA (h) Lentiviral Particles - sc-91418-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULA/STS-2 RNAi - H00053347-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TULA/STS-2 RNAi - H00053347-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU069551 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22348 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22348 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04576 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04576

UBASH3A siRNA (Human) - CRH9965 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBASH3A - MBS8235979 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBASH3A (NM_018961.3) - SHH438772 from Creative biogene

Category siRNA
Species Reactivities Human

UBASH3A shRNA Plasmid (Human) - CHH9965 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBASH3A miRNA 3'UTR clone - MiUTR3H-07920 from Creative biogene

Species Reactivities Human

UBASH3A miRNA 3'UTR clone - MiUTR3H-07921 from Creative biogene

Species Reactivities Human
Search more