CUL2

Gene Symbol	CUL2
Entrez Gene	8453
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	cullin 2
Other Description	CUL-2|cullin-2
Swissprots	Q5T2B6 G3V1S2 B7Z6K8 O00200 Q13617 Q9UNF9 D3DRY6 B3KT95
Accessions	EAW85922 EAW85924 EAW85925 EAW85926 EAW85927 EAW85928 Q13617 AF126404 AAD23581 AI089201 AK095217 BAG53007 AK294080 BAH11667 AK300491 BAH13294 AK310225 AL832733 BC009591 AAH09591 BC095405 BC110901 AAI10902 DC401811 DC401936 HG502803 HG502804 HG502805 JF432297 ADZ15514 U58088 AAC50545 U83410 AAC51190 XM_011519743 XP_011518045 XM_011519744 XP_011518046 XM_011519745 XP_011518047 XM_011519746 XP_011518048 XM_011519747 XP_011518049 NM_001198777 NP_001185706 NM_001198778 NP_001185707 NM_001198779 NP_001185708 NM_003591 NP_003582
Function	Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). {ECO:0000250}.
Top Pathways	Ubiquitin mediated proteolysis, Renal cell carcinoma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human CUL2 / Cullin 2 ELISA Kit (Cell-Based ELISA) - LS-F1921 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Cullin-2 (CUL2), Human, ELISA Kit - E01C2182 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/ml

Cullin 2 Colorimetric Cell-Based ELISA Kit - CB5180 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Cullin 2 (CUL2), ELISA Kit - MBS7223818 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin 2 (CUL2), ELISA Kit - MBS9312429 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7241231 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7229975 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7227416 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7252530 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7237171 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7215413 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7239991 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7222844 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7227572 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7241406 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-2 (CUL2), ELISA Kit - MBS7243475 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin 2 ELISA Kit - DEIA-XYA491 from Creative Diagnostics Category ELISA Kit

Human CUL2 ELISA Kit - E010380 from Biobool Category ELISA Kit

anti-Cullin-2 (CUL-2) antibody - ARG52915 from Arigo Biolaboratories Category ELISA Kit

anti-CUL2 antibody - ARG65236 from Arigo Biolaboratories Category ELISA Kit

anti-Cullin-2 (CUL-2) antibody (Ready-to-Use) - ARG52916 from Arigo Biolaboratories Category ELISA Kit

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