UFD1L

Gene Symbol UFD1L
Entrez Gene 7353
Alt Symbol UFD1
Species Human
Gene Type protein-coding
Description ubiquitin fusion degradation 1 like (yeast)
Other Description UB fusion protein 1|ubiquitin fusion degradation protein 1 homolog
Swissprots Q92890 Q9Y5N0 A8MW31
Accessions EAX03037 EAX03038 Q92890 AF141201 AAD28788 AJ239058 CAC20414 AK128120 AK225877 AK304734 BAG65495 AK308786 AK310950 AK315998 BAH14369 AM392868 CAL37746 AW131352 AY101594 AAM48288 BC001049 AAH01049 BC005087 AAH05087 BM761958 BX648374 BX648483 CB128364 CR456607 CAG30493 CU013203 CAK54634 CU013491 CAK54933 DB496066 DB570679 U64444 AAD08720 XM_005261277 XP_005261334 XM_006724319 XP_006724382 XM_011530361 XP_011528663 XM_011530362 XP_011528664 XM_011530363 XP_011528665 NM_001035247 NP_001030324 NM_005659 NP_005650
Function Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Found in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney.
Top Pathways Protein processing in endoplasmic reticulum

Ubiquitin fusion degradation protein 1 homolog (UFD1L), Human, ELISA Kit - CSB-EL025559HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 15.6 pg/ml
Range 62.5 pg/ml-4000 pg/ml

ubiquitin fusion degradation 1 like (yeast) , ELISA Kit - MBS915610 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 15.6 pg/ml
Range 62.5 pg/ml-4000 pg/ml

Human Ubiquitin fusion degradation protein 1 homolog(UFD1L) ELISA kit - CSB-EL025559HU from Cusabio

Category ELISA Kit
Sensitivity 15.6pg/ml
Range 62.5 pg/ml-4000 pg/ml

Human UFD1L ELISA Kit - E040286 from Biobool

Category ELISA Kit
Sensitivity 15.6 pg/ml

UFD1L ELISA Kit (Human) (OKCA01582) - OKCA01582 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 15.6 pg/mL
Range 62.5 - 4,000 pg/mL

Human UFD1L ELISA Kit - orb405510 from Biorbyt

Category ELISA Kit
Sensitivity 15.6pg/ml
Range 62.5 pg/ml-4000 pg/ml
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