UFD1L

Gene Symbol UFD1L
Entrez Gene 7353
Alt Symbol UFD1
Species Human
Gene Type protein-coding
Description ubiquitin fusion degradation 1 like (yeast)
Other Description UB fusion protein 1|ubiquitin fusion degradation protein 1 homolog
Swissprots Q92890 Q9Y5N0 A8MW31
Accessions EAX03037 EAX03038 Q92890 AF141201 AAD28788 AJ239058 CAC20414 AK128120 AK225877 AK304734 BAG65495 AK308786 AK310950 AK315998 BAH14369 AM392868 CAL37746 AW131352 AY101594 AAM48288 BC001049 AAH01049 BC005087 AAH05087 BM761958 BX648374 BX648483 CB128364 CR456607 CAG30493 CU013203 CAK54634 CU013491 CAK54933 DB496066 DB570679 U64444 AAD08720 XM_005261277 XP_005261334 XM_006724319 XP_006724382 XM_011530361 XP_011528663 XM_011530362 XP_011528664 XM_011530363 XP_011528665 NM_001035247 NP_001030324 NM_005659 NP_005650
Function Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Found in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney.
Top Pathways Protein processing in endoplasmic reticulum

UFD1 Antibody - 13789 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using UFD1 Antibody.

UFD1 (B-7) - sc-377265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UFD1 (B-7): sc-377265. Western blot analysis of UFD1 expression in non-transfected 293T: sc-117752 (A), mouse UFD1 transfected 293T: sc-124444 (B) and K-562 (C) whole cell lysates.

UFD1 (C-20) - sc-9296 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UFD1 (C-20): sc-9296. Western blot analysis of UFD1 expression in non-transfected: sc-117752 (A) and mouse UFD1 transfected: sc-124444 (B) 293T whole cell lysates.

UFD1 (E-4) - sc-271221 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UFD1 (E-4): sc-271221. Western blot analysis of UFD1 expression in non-transfected: sc-117752 (A) and mouse UFD1 transfected: sc-124444 (B) 293T whole cell lysates.

UFD1 (E-9) - sc-377222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UFD1 (E-9): sc-377222. Western blot analysis of UFD1 expression in non-transfected 293T: sc-117752 (A), mouse UFD1 transfected 293T: sc-124444 (B) and K-562 (C) whole cell lysates.

UFD1 (H-127) - sc-292639 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UFD1 (H-127): sc-292639. Western blot analysis of UFD1 expression in non-transfected 293T: sc-117752 (A), mouse UFD1 transfected 293T: sc-124444 (B) and K-562 (C) whole cell lysates.

UFD1 (N-19) - sc-9295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UFD1 (N-19): sc-9295. Western blot analysis of UFD1 expression in non-transfected: sc-117752 (A) and mouse UFD1 transfected: sc-124444 (B) 293T whole cell lysates.

UFD1 (5e2) - sc-81630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UFD1 (5e2): sc-81630. Western blot analysis of UFD1 expression in HeLa whole cell lysate.

UFD1 (19) - sc-136114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
UFD1 (19): sc-136114. Western blot analysis of UFD1 expression in mouse macrophage tissue extract.

Anti-UFD1L antibody - ab96648 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-UFD1L antibody (ab96648) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-UFD1L antibody - ab155003 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of methanol-fixed A431 cells, labeling UFD1L with ab155003 at 1/200 dilution. Lower image shows costaining with Hoechst 33342.

Anti-UFD1L antibody - ab56208 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UFD1L antibody [5e2] - ab52094 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5e2

Anti-UFD1L antibody [EPR12847] - N-terminal - ab181080 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12847
All lanes : Anti-UFD1L antibody [EPR12847] - N-terminal (ab181080) at 1/2000 dilutionLane 1 : Raji cell lysateLane 2 : HeLa cell lysateLysates/proteins at 1/1000 dilution per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-UFD1L Antibody (C-Terminus) - LS-C46965 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UFD1L Antibody (aa175-225) - LS-C288653 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD1L Antibody (aa257-307) - LS-C288657 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD1L Antibody (clone 3F1) - LS-C339060 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UFD1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UFD1L.

Anti-UFD1L Antibody (clone 3E9) - LS-C339122 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UFD1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UFD1L.

Anti-UFD1L Antibody (aa161-210) - LS-C116851 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UFD1L antibody LS-C116851 Western blot of MCF7 cell lysate.

Anti-UFD1L Antibody - LS-C334942 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using UFD1L antibody.

Anti-UFD1L Antibody (clone 3A12) - LS-C339119 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UFD1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UFD1L.

Anti-UFD1L Antibody (clone 3B4) - LS-C339132 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UFD1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UFD1L.

Anti-UFD1L Antibody (clone 4C7) - LS-C339125 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C7
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-UFD1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-UFD1L Antibody (clone 5E3) - LS-C339134 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5E3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UFD1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UFD1L.
Search more