Gene Symbol | NAT10 |
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Entrez Gene | 55226 |
Alt Symbol | ALP, NET43 |
Species | Human |
Gene Type | protein-coding |
Description | N-acetyltransferase 10 (GCN5-related) |
Other Description | N-acetyltransferase 10|N-acetyltransferase-like protein |
Swissprots | Q9H0A0 Q9NVF2 Q9C0F4 Q9HA61 E9PMN9 Q86WK5 E7ESU4 B4DFD5 |
Accessions | EAW68174 EAW68175 Q9H0A0 AB051496 BAB21800 AF489535 AAO49126 AK001636 BAA91800 AK022241 BAB13995 AK074430 AK225341 AK294044 BAG57396 AL136882 CAB66816 AM393096 CAL37974 BC014440 BC020205 AAH20205 BC035558 AAH35558 BM988569 CN336530 XM_011520197 XP_011518499 NM_001144030 NP_001137502 NM_024662 NP_078938 |
Function | Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. {ECO:0000269|PubMed:14592445, ECO:0000269|PubMed:17631499, ECO:0000269|PubMed:18082603, ECO:0000269|PubMed:19303003}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:14592445, ECO:0000269|PubMed:19303003}. Note=Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase. |
Top Pathways | Ribosome biogenesis in eukaryotes |
NAT-10 (B-4) - sc-271770 from Santa Cruz Biotechnology
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NAT-10 (C-10) - sc-271141 from Santa Cruz Biotechnology
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NAT-10 (D-11) - sc-271771 from Santa Cruz Biotechnology
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NAT-10 (D-5) - sc-271142 from Santa Cruz Biotechnology
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NAT-10 (H-300) - sc-135039 from Santa Cruz Biotechnology
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NAT-10 (P-16) - sc-65143 from Santa Cruz Biotechnology
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Anti-NAT10 antibody - ab197259 from Abcam
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Anti-NAT10 Antibody (aa917-928) IHC-plus⢠- LS-B4935 from LifeSpan Bioscience
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Anti-NAT10 Antibody - LS-C346335 from LifeSpan Bioscience
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Anti-NAT10 Antibody - LS-C334438 from LifeSpan Bioscience
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Anti-NAT10 Antibody (aa650-700) - LS-C291022 from LifeSpan Bioscience
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NAT10 Antibody - NBP2-15034 from Novus Biologicals
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NAT10 Antibody - NBP2-32263 from Novus Biologicals
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NAT10 Antibody - NBP1-06055 from Novus Biologicals
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NAT10 Antibody - NBP2-15033 from Novus Biologicals
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NAT10 Antibody - H00055226-A01 from Novus Biologicals
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NAT10 Polyclonal Antibody - bs-7757R from Bioss
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Anti-NAT10 antibody produced in goat - SAB2501798 from Sigma-Aldrich
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Anti-NAT10 (171-185) antibody produced in rabbit - SAB1102021 from Sigma-Aldrich
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Anti-NAT10 (N-terminal) antibody produced in rabbit - SAB2700591 from Sigma-Aldrich
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Anti-NAT10 antibody produced in rabbit - SAB2700592 from Sigma-Aldrich
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NAT10--hALP-Antibody-internal-region-near-the-C-Term - AF2566a from Abgent, a WuXi AppTec company
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NAT10 antibody - GTX119167 from GeneTex
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NAT10 antibody [N1N2], N-term - GTX119166 from GeneTex
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Goat Anti-NAT10 / hALP Antibody (OAEB00645) - OAEB00645 from Aviva Systems Biology
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