NAT10

Gene Symbol NAT10
Entrez Gene 55226
Alt Symbol ALP, NET43
Species Human
Gene Type protein-coding
Description N-acetyltransferase 10 (GCN5-related)
Other Description N-acetyltransferase 10|N-acetyltransferase-like protein
Swissprots Q9H0A0 Q9NVF2 Q9C0F4 Q9HA61 E9PMN9 Q86WK5 E7ESU4 B4DFD5
Accessions EAW68174 EAW68175 Q9H0A0 AB051496 BAB21800 AF489535 AAO49126 AK001636 BAA91800 AK022241 BAB13995 AK074430 AK225341 AK294044 BAG57396 AL136882 CAB66816 AM393096 CAL37974 BC014440 BC020205 AAH20205 BC035558 AAH35558 BM988569 CN336530 XM_011520197 XP_011518499 NM_001144030 NP_001137502 NM_024662 NP_078938
Function Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. {ECO:0000269|PubMed:14592445, ECO:0000269|PubMed:17631499, ECO:0000269|PubMed:18082603, ECO:0000269|PubMed:19303003}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:14592445, ECO:0000269|PubMed:19303003}. Note=Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase.
Top Pathways Ribosome biogenesis in eukaryotes

NAT-10 (B-4) - sc-271770 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NAT-10 (B-4): sc-271770. Western blot analysis of NAT-10 expression in HeLa nuclear extract.

NAT-10 (C-10) - sc-271141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NAT-10 (C-10): sc-271141. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar localization.

NAT-10 (D-11) - sc-271771 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NAT-10 (D-11): sc-271771. Western blot analysis of NAT-10 expression in HeLa nuclear extract.

NAT-10 (D-5) - sc-271142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NAT-10 (D-5): sc-271142. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.

NAT-10 (H-300) - sc-135039 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NAT-10 (H-300): sc-135039. Western blot analysis of NAT-10 expression in PMA treated Jurkat (A), MCF7 (B) and K-562 (C) whole cell lysates.

NAT-10 (P-16) - sc-65143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NAT-10 (P-16): sc-65143. Western blot analysis of NAT-10 expression in non-transfected: sc-117752 (A) and mouse NAT-10 transfected: sc-127198 (B) 293T whole cell lysates.

Anti-NAT10 antibody - ab197259 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-NAT10 antibody (ab197259) at 1/500 dilution + HeLa cell lysates

Anti-NAT10 Antibody (aa917-928) IHC-plus™ - LS-B4935 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-NAT10 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4935 concentration 3.75 ug/ml.

Anti-NAT10 Antibody - LS-C346335 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using NAT10 antibody. Blue: DAPI for nuclear staining.

Anti-NAT10 Antibody - LS-C334438 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NAT10 antibody.

Anti-NAT10 Antibody (aa650-700) - LS-C291022 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human NAT10 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from 293T cells. Antibodies: Affinity purified rabbit anti-NAT10 antibody used for IP at 6 ug per reaction. NAT10 was also immunoprecipitated by rabbit anti-NAT10 antibody BL15900. For blotting immunoprecipitated NAT10, was used at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

NAT10 Antibody - NBP2-15034 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NAT10 Antibody [NBP2-15034] - Sample (30 ug of whole cell lysate) A: MCF-7 7.5% SDS PAGE; antibody diluted at 1:1000.

NAT10 Antibody - NBP2-32263 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NAT10 Antibody - NBP1-06055 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: NAT10 Antibody [NBP1-06055] - (3.8ug/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

NAT10 Antibody - NBP2-15033 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NAT10 Antibody [NBP2-15033] - Sample (30 ug of whole cell lysate) A: Hela 7. 5% SDS PAGE; antibody diluted at 1:1000.

NAT10 Antibody - H00055226-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

NAT10 Polyclonal Antibody - bs-7757R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NAT10 antibody produced in goat - SAB2501798 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NAT10 (171-185) antibody produced in rabbit - SAB1102021 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NAT10 was separated on SDS-PAGE, blotted with Anti-NAT10 (171-185) (<B>Cat. No. SAB1102021</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-NAT10 (N-terminal) antibody produced in rabbit - SAB2700591 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NAT10 (N-terminal): <B>Cat. No. SAB2700591</B>: Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using NAT10 antibody at 1:100 dilution.

Anti-NAT10 antibody produced in rabbit - SAB2700592 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NAT10: <B>Cat. No. SAB2700592</B>: Western Blot analysis of NAT10 in extracts from <B>Lanes</B><BR/>A. HeLa using <B>Cat. No. SAB2700592</B> at a 1:1000 dilution.

NAT10--hALP-Antibody-internal-region-near-the-C-Term - AF2566a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2566a (3.8 µg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

NAT10 antibody - GTX119167 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal

NAT10 antibody [N1N2], N-term - GTX119166 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-NAT10 antibody [N1N2], N-term used in ICC/IF. GTX119166

Goat Anti-NAT10 / hALP Antibody (OAEB00645) - OAEB00645 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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