APLN

Gene Symbol APLN
Entrez Gene 8862
Alt Symbol APEL, XNPEP2
Species Human
Gene Type protein-coding
Description apelin
Other Description AGTRL1 ligand|APJ endogenous ligand
Swissprots Q8WU89 Q9ULZ1 Q4VY08
Accessions AAF25815 EAX11828 EAX11829 Q9ULZ1 AB023493 BAA84975 AF086248 AK001855 AK312061 BAG34997 AY358657 AAQ89020 BC021104 AAH21104 BM992527 DB481574 DQ892125 ABM83051 DQ895318 ABM86244 NM_017413 NP_059109
Function Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior. {ECO:0000269|PubMed:11090199}.
Subcellular Location Secreted.
Tissue Specificity Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.

Apelin CRISPR/Cas9 KO Plasmid (h) - sc-401548 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin HDR Plasmid (h) - sc-401548-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin Double Nickase Plasmid (h) - sc-401548-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin Double Nickase Plasmid (h2) - sc-401548-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin CRISPR Activation Plasmid (h) - sc-401548-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin CRISPR Activation Plasmid (h2) - sc-401548-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin Lentiviral Activation Particles (h) - sc-401548-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin Lentiviral Activation Particles (h2) - sc-401548-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Apelin siRNA (h) - sc-44741 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Apelin shRNA Plasmid (h) - sc-44741-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Apelin shRNA (h) Lentiviral Particles - sc-44741-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Apelin RNAi - H00008862-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU071861 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN3323 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3323 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

APLN siRNA (Human) - CRH5853 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APLN - MBS8207675 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APLN (NM_017413.4) - SHH238270 from Creative biogene

Category siRNA
Species Reactivities Human

Human APLN siRNA - orb266355 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APLN shRNA Plasmid (Human) - CHH5853 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APLN miRNA 3'UTR clone - MiUTR4H-TG00407 from Creative biogene

Species Reactivities Human
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