APLN

Gene Symbol	APLN
Entrez Gene	8862
Alt Symbol	APEL, XNPEP2
Species	Human
Gene Type	protein-coding
Description	apelin
Other Description	AGTRL1 ligand|APJ endogenous ligand
Swissprots	Q8WU89 Q9ULZ1 Q4VY08
Accessions	AAF25815 EAX11828 EAX11829 Q9ULZ1 AB023493 BAA84975 AF086248 AK001855 AK312061 BAG34997 AY358657 AAQ89020 BC021104 AAH21104 BM992527 DB481574 DQ892125 ABM83051 DQ895318 ABM86244 NM_017413 NP_059109
Function	Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior. {ECO:0000269|PubMed:11090199}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Apelin full length protein - ab152926 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human Apelin full length protein - ab152927 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Recombinant Human Apelin Protein - H00008862-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Apelin Protein - H00008862-P02 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Apelin Blocking Peptide - abx161272 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken

Human Apelin Protein - abx065397 from Abbexa Category Protein Source E.coli Species Human

Human Apelin Protein - abx065395 from Abbexa Category Protein Source E.coli Species Human

Apelin - H00008862-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Apelin - H00008862-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Apelin - H00008862-P02-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Apelin - H00008862-P02-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

Apelin (APLN), Human - 20-8651 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

Apelin (APLN), Human - 20-8652 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

APLN fusion protein - ag14447 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

APLN fusion protein - ag2047 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Apelin-13 Peptide - 350066 from ABBIOTEC Category Peptide Prices $90.00 Sizes 1 mg

Recombinant Human APLN, His-tagged, S tagged - APLN-3549H from Creative Biomart Category Protein Source E. Coli Species Human

Recombinant Apelin (APLN) - RPD066Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Apelin (APLN) - RPD066Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Apelin (APLN) - RPD066Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Apelin (APLN) - RPD066Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Apelin (APLN) - RPD066Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Apelin 12, Asp5, des Pro12, des Phe13 - 000-001-M17 from Rockland Immunochemicals Inc Category Peptide Prices $67.00 Sizes 1 mg

Apelin 12, Asp5, des Pro12, des Phe13 - 000-001-M17L from Rockland Immunochemicals Inc Category Peptide Prices $265.00 Sizes 5 mg

Apelin 12, human, bovine, rat, mouse - 000-001-L59 from Rockland Immunochemicals Inc Category Peptide Prices $67.00 Sizes 1 mg Species Human

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