CRB3

Gene Symbol CRB3
Entrez Gene 92359
Alt Symbol -
Species Human
Gene Type protein-coding
Description crumbs family member 3
Other Description crumbs homolog 3|crumbs protein homolog 3|protein crumbs homolog 3
Swissprots Q8N0V8 Q8WVA0 A8KA91 Q9BUF7 D6W643
Accessions EAW69083 EAW69084 EAW69085 EAW69086 Q9BUF7 AF503290 AAM23013 AK000653 AK292956 BAF85645 AY103469 AAM44074 AY358684 AAQ89047 BC002652 AAH02652 BC018409 AAH18409 BM129809 CN403242 XM_005259680 XP_005259737 NM_139161 NP_631900 NM_174881 NP_777377
Function Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions. {ECO:0000269|PubMed:12771187, ECO:0000269|PubMed:14718572}.
Subcellular Location Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
Tissue Specificity Preferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate. {ECO:0000269|PubMed:12527193, ECO:0000269|PubMed:14718572}.
Top Pathways Tight junction

Human CRB3 full length protein - ab164906 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164906 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CRB3 Antibody Blocking Peptide - LS-E5135 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CRB3 Protein - H00092359-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CRB3-Antibody-Center-Blocking-Peptide - BP17560c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Crumbs homolog 3 - H00092359-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Crumbs homolog 3 - H00092359-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CRB3 fusion protein - Ag2968 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CRB3, GST-tagged - CRB3-11555H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Crumbs protein homolog 3(CRB3) - CSB-YP866285HU CSB-EP866285HU CSB-BP866285HU CSB-MP866285HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CRB3 Recombinant Protein Antigen - NBP1-81185PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CRB3 Peptide, Human - M34GP03615H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

CRB3 fusion protein - Ag26303 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

CRB3 fusion protein - Ag25981 from Proteintech Group

Category Protein
Source E. coli -derived, PGEX-4T
Species Human
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