UGT2B4

Gene Symbol	UGT2B4
Entrez Gene	7363
Alt Symbol	HLUG25, UDPGT2B4, UDPGTH1, UDPGTh-1, UGT2B11
Species	Human
Gene Type	protein-coding
Description	UDP glucuronosyltransferase 2 family, polypeptide B4
Other Description	UDP-glucuronosyltransferase 2B4|UDP-glucuronyltransferase, family 2, beta-4|UDPGT 2B4|hyodeoxycholic acid|hyodeoxycholic acid-specific UDPGT
Swissprots	A6NCP7 G5E9X8 O60867 Q1HBF9 P06133 O75614 O60731 Q6QQX7 P36538 B4DT75
Accessions	AAF78145 ABF47107 EAX05591 EAX05592 P06133 AF064200 AAC95002 AF081793 AAC32272 AJ005162 CAA06396 AK292748 BAF85437 AK300084 BAG61887 AY529122 AAS47487 BC026264 AAH26264 BX494777 DB185148 DQ895203 ABM86129 Y00317 CAA68415 XM_005265701 XP_005265758 NM_001297615 NP_001284544 NM_001297616 NP_001284545 NM_021139 NP_066962
Function	UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Subcellular Location	Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Top Pathways	Chemical carcinogenesis, Bile secretion, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UGT2B (E-6) - sc-271777 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

UGT2B (H-300) - sc-50386 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

UGT2B (F-17) - sc-23479 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-UGT2B4 antibody - ab76626 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-UGT2B4 antibody [EPR11677] - ab173580 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR11677

Anti-UGT2B4 antibody - N-terminal - ab156229 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa38-87) - LS-C81415 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96) - LS-C157018 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (clone 2H6) - LS-C198406 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2H6

Anti-UGT2B4 Antibody (aa68-96, AP) - LS-C218263 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96, APC) - LS-C218264 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96, Biotin) - LS-C218267 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96, FITC) - LS-C218268 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96, Azide-free, HRP) - LS-C218269 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96, PE) - LS-C218270 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 Antibody (aa68-96) - LS-C326176 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

UGT2B4 Antibody - NBP1-69604 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

UGT2B4 Antibody (2H6) - H00007363-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2H6

UGT2B4 Polyclonal Antibody - bs-4225R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-UGT2B4 antibody produced in rabbit - SAB2102645 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Monoclonal Anti-UGT2B4 antibody produced in mouse - SAB1402387 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2H6

UGT2B4 antibody - N-terminal region (ARP49624_P050) - ARP49624_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

UGT2B4-AntibodyN-term - AP19747a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

UGT2B4 Antibody - N-terminal region (OAAB15247) - OAAB15247 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

UGT2B4 antibody - 70R-21156 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

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