AHR

Gene Symbol AHR
Entrez Gene 196
Alt Symbol bHLHe76
Species Human
Gene Type protein-coding
Description aryl hydrocarbon receptor
Other Description AH-receptor|ah receptor|aromatic hydrocarbon receptor|class E basic helix-loop-helix protein 76
Swissprots Q13803 Q13728 A4D130 Q13804 P35869
Accessions AAA92082 AAA92083 AAA92084 BAA07235 CCO13674 EAL24281 EAW93686 EAW93687 P35869 AA329775 AK130815 AK307495 BC021696 BC069390 AAH69390 BC070080 AAH70080 BQ020427 BQ024331 BX505160 D16354 BAA03857 L19872 AAA16210 NM_001621 NP_001612
Function Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. {ECO:0000269|PubMed:10395741, ECO:0000269|PubMed:7961644}.
Subcellular Location Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Tissue Specificity Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. {ECO:0000269|PubMed:7515333, ECO:0000269|PubMed:8246913}.

AHR - MBS1266053 from MyBioSource

Species Human
Accession BC069390

Human AHR ORF Clone(NM_001621.4) - CDCL153401 from Creative Biomart

Species Human
Accession NM_001621.4

Human AHR Gene cDNA Clone (full-length ORF Clone) - HG10456-M from Sino Biological

Species Human
Accession NM_001621.3

Human AHR natural ORF mammalian expression plasmid, C-Flag tag - HG10456-CF from Sino Biological

Species Human
Accession NM_001621.3

Human AHR natural ORF mammalian expression plasmid, N-OFPSpark tag - HG10456-ANR from Sino Biological

Species Human
Accession NM_001621.3

Human AHR natural ORF mammalian expression plasmid, N-GFPSpark tag - HG10456-ANG from Sino Biological

Species Human
Accession NM_001621.3

Human AHR natural ORF mammalian expression plasmid, N-His tag - HG10456-NH from Sino Biological

Species Human
Accession NM_001621.3

Human AHR natural ORF mammalian expression plasmid, N-Flag tag - HG10456-NF from Sino Biological

Species Human
Accession NM_001621.3

Human AHR ORF Clone (BC069390) - CDCS410339 from Creative biogene

Species Human
Accession P35869

Human AHR ORF clone (NM_001621.3) - CDCB157541 from Creative biogene

Species Human

Human AHR gene - orb91040 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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