AHR

Gene Symbol	AHR
Entrez Gene	196
Alt Symbol	bHLHe76
Species	Human
Gene Type	protein-coding
Description	aryl hydrocarbon receptor
Other Description	AH-receptor\|ah receptor\|aromatic hydrocarbon receptor\|class E basic helix-loop-helix protein 76
Swissprots	Q13803 Q13728 A4D130 Q13804 P35869
Accessions	AAA92082 AAA92083 AAA92084 BAA07235 CCO13674 EAL24281 EAW93686 EAW93687 P35869 AA329775 AK130815 AK307495 BC021696 BC069390 AAH69390 BC070080 AAH70080 BQ020427 BQ024331 BX505160 D16354 BAA03857 L19872 AAA16210 NM_001621 NP_001612
Function	Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. {ECO:0000269\|PubMed:10395741, ECO:0000269\|PubMed:7961644}.
Subcellular Location	Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Tissue Specificity	Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. {ECO:0000269\|PubMed:7515333, ECO:0000269\|PubMed:8246913}.

AhR Antibody - 13790 from Cell Signaling Technology

Prices	$239.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts from various cell lines using AhR Antibody.

Ah Receptor (A-3) - sc-133088 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Ah Receptor (A-3): sc-133088. Western blot analysis of Ah Receptor expression in HeLa (A) and PC-3 (B) whole cell lysates.

Ah Receptor (C-18) - sc-8087 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Ah Receptor (C-18): sc-8087. Western blot analysis of Ah Receptor expression in PC-3 whole cell lysate.

Ah Receptor (N-19) - sc-8088 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Ah Receptor (N-19): sc-8088. Western blot analysis of Ah Receptor expression in HeLa whole cell lysate.

Ah Receptor (H-211) - sc-5579 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Ah Receptor (H-211): sc-5579. Western blot analysis of Ah Receptor expression in PC-3 whole cell lysate.

Ah Receptor (L-15) - sc-101104 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

Ah Receptor (L-15): sc-101104. Western blot analysis of Ah Receptor expression in COLO 320 HSR whole cell lysate.

Anti-Aryl hydrocarbon Receptor (phospho S36) antibody - ab182642 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Aryl hydrocarbon Receptor (phospho S36) antibody (ab182642) at 1/500 dilutionLane 1 : HepG2 cell lysate with immunizing peptideLane 2 : HepG2 cell lysate

Anti-Aryl hydrocarbon Receptor (phospho S36) antibody - ab195752 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Aryl hydrocarbon Receptor (phospho S36) antibody (ab195752) at 1/500 dilutionLane 1 : HepG2 whole cell lysates with antigen-specific peptideLane 2 : HepG2 whole cell lysatesLysates/proteins at 12.5 µg per lane.

Anti-Aryl hydrocarbon Receptor antibody - ab84833 from Abcam

Prices	$394.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Aryl hydrocarbon Receptor antibody (ab84833) at 1/200 dilution + HepG2 cell lysate

Anti-Aryl hydrocarbon Receptor antibody - ab153744 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Aryl hydrocarbon Receptor antibody (ab153744) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Aryl hydrocarbon Receptor antibody - ab186070 from Abcam

Prices	$376.00
Sizes	200 µl
Host	Goat
Clonality	Polyclonal

Immunohistochemical analysis of paraffin embedded Human kidney tissue staining Aryl hydrocarbon Receptor using ab186070 at 2µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Anti-Aryl hydrocarbon Receptor antibody [3B9] - ab124222 from Abcam

Prices	$376.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B9

ab124222, at 5 µg/ml, staining Aryl hydrocarbon Receptor in formalin fixed, paraffin embedded Human placenta tissue by Immunohistochemistry.

Anti-Aryl hydrocarbon Receptor antibody [EPR7119(N)(2)] - ab190797 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR7119(N)(2)

All lanes : Anti-Aryl hydrocarbon Receptor antibody [EPR7119(N)(2)] (ab190797) at 1/5000 dilutionLane 1 : 293 cell lysateLane 2 : Caco-2 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Aryl hydrocarbon Receptor antibody [RPT1] - ChIP Grade - ab2770 from Abcam

Prices	$394.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	RPT1

Immunofluorescent analysis of Aryl Hydrocarbon Receptor in NIH-3T3 cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control, right) or with a Aryl Hydrocarbon Receptor monoclonal antibody (ab2770, left) at a dilution of 1:200 overnight at 4 C and incubated with a DyLight-488 conjugated secondary antibody. Aryl Hydrocarbon Receptor staining (green) F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

Anti-Aryl hydrocarbon Receptor antibody [RPT9] - ChIP Grade - ab2769 from Abcam

Prices	$395.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	RPT9

Immunocytochemistry/Immunofluorescence analysis of Aryl Hydrocarbon Receptor shows staining in A2058 cells. Aryl Hydrocarbon Receptor (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were incubated without (control) or with ab2769 (1:20) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Images were taken at 60X magnification.

Anti-Aryl hydrocarbon Receptor antibody - N-terminal - ab135917 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Aryl hydrocarbon Receptor antibody - N-terminal (ab135917) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-Aryl hydrocarbon Receptor antibody - ab28698 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Aryl hydrocarbon Receptor antibody (ab28698) at 2.5 µg/ml + Human placental lysateSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilutionObserved band size : 85 kDa (why is the actual band size different from the predicted?)

Anti-Aryl hydrocarbon Receptor antibody - ab49351 from Abcam

Prices	$378.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Aryl hydrocarbon Receptor antibody (ab49351) at 2.5 µg/ml + HepG2 cell lysate at 10 µg with 5% skim milk in PBS.SecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-AHR Antibody (N-Terminus) - LS-C2608 from LifeSpan Bioscience

Prices	$335.00
Sizes	1 ml
Host	Goat
Clonality	Polyclonal

Anti-AHR Antibody (aa101-118) - LS-C2984 from LifeSpan Bioscience

Prices	$265.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AHR Antibody (aa828-844) - LS-C2985 from LifeSpan Bioscience

Prices	$265.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AHR Antibody (N-Terminus) - LS-C20353 from LifeSpan Bioscience

Prices	$530.00
Sizes	1 ml
Host	Goat
Clonality	Polyclonal

Anti-AHR Antibody (N-Terminus) - LS-C31440 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AHR Antibody (aa18-21, clone RPT9) - LS-C63836 from LifeSpan Bioscience

Prices	$560.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	RPT9

Anti-AHR Antibody - LS-C121351 from LifeSpan Bioscience

Prices	$695.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

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