DACH2

Gene Symbol	DACH2
Entrez Gene	117154
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	dachshund family transcription factor 2
Other Description	dachshund homolog 2
Swissprots	Q8NAY3 Q8ND17 B4DQG3 B1AJV3 Q96N55 Q96NX9
Accessions	EAW98554 EAW98555 EAW98556 Q96NX9 AF428101 AAL26561 AK055953 BAB71054 AK091842 BAC03761 AK290596 BAF83285 AK294498 BAG57717 AK295648 BAG58518 AK298787 BAG60925 AL834456 CAD39116 BC040213 BC048423 BC114950 AAI14951 XM_011530846 XP_011529148 XM_011530847 XP_011529149 XM_011530848 XP_011529150 NM_001139514 NP_001132986 NM_001139515 NP_001132987 NM_053281 NP_444511
Function	Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression (By similarity). Probably binds to DNA via its DACHbox-N domain. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DACH2 Antibody Blocking Peptide - LS-E2299 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH2 Antibody Blocking Peptide - LS-E11356 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH2 Antibody Blocking Peptide - LS-E26645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DACH2-Antibody-N-term-Blocking-peptide - BP13241a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Dachshund homolog 2/DACH2 blocking peptide - GTX88789-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

DACH2 Blocking Peptide - 33R-9147 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DACH2 Peptide - AC21-1481-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DACH2 Peptide - 46-650P from ProSci Category Peptide Species Mouse

DACH2 fusion protein - Ag18186 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

DACH2 fusion protein - Ag18403 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DACH2, His-tagged - DACH2-11816H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Dachshund homolog 2(DACH2) - CSB-YP839385HU CSB-EP839385HU CSB-BP839385HU CSB-MP839385HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DACH2 (transcript variant 3) - TP327811 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Dachshund homolog 2/DACH2, Peptide - MBS426947 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

DACH2 Recombinant Protein Antigen - NBP1-89476PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DACH2 Peptide, Human - M34GP04009H from Creative Peptides Category Peptide Source Synthetic. Species Human

DACH2, Recombinant Protein - MBS286214 from MyBioSource Category Protein Prices $380.00, $1,065.00, $1,485.00 Sizes 100 µg, 500 µg, 1 mg Source E Coli

Dachshund homolog 2 (DACH2), Recombinant Protein - MBS1346369 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,620.00, $1,620.00, $2,340.00, $2,340.00, $2,785.00, $2,785.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human DACH2 Protein, GST-tagged - DACH2-2321H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human DACH2 Protein, MYC/DDK-tagged - DACH2-992H from Creative Biomart Category Protein Source HEK293 Species Human

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