DACH2

Gene Symbol DACH2
Entrez Gene 117154
Alt Symbol -
Species Human
Gene Type protein-coding
Description dachshund family transcription factor 2
Other Description dachshund homolog 2
Swissprots Q8NAY3 Q8ND17 B4DQG3 B1AJV3 Q96N55 Q96NX9
Accessions EAW98554 EAW98555 EAW98556 Q96NX9 AF428101 AAL26561 AK055953 BAB71054 AK091842 BAC03761 AK290596 BAF83285 AK294498 BAG57717 AK295648 BAG58518 AK298787 BAG60925 AL834456 CAD39116 BC040213 BC048423 BC114950 AAI14951 XM_011530846 XP_011529148 XM_011530847 XP_011529149 XM_011530848 XP_011529150 NM_001139514 NP_001132986 NM_001139515 NP_001132987 NM_053281 NP_444511
Function Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression (By similarity). Probably binds to DNA via its DACHbox-N domain. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.

DACH2 CRISPR/Cas9 KO Plasmid (h) - sc-414105 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 HDR Plasmid (h) - sc-414105-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 Double Nickase Plasmid (h) - sc-414105-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 Double Nickase Plasmid (h2) - sc-414105-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 CRISPR Activation Plasmid (h) - sc-414105-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 CRISPR Activation Plasmid (h2) - sc-414105-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 Lentiviral Activation Particles (h) - sc-414105-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 Lentiviral Activation Particles (h2) - sc-414105-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DACH2 siRNA (h) - sc-77091 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DACH2 shRNA Plasmid (h) - sc-77091-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DACH2 shRNA (h) Lentiviral Particles - sc-77091-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DACH2 RNAi - H00117154-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU157811 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6913 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6913 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DACH2 siRNA (Human) - CRJ4551 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DACH2 - MBS8210994 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DACH2 (NM_053281.3) - SHH274361 from Creative biogene

Category siRNA
Species Reactivities Human

Human DACH2 siRNA - orb275052 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DACH2 shRNA Plasmid (Human) - CHJ4551 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DACH2 miRNA 3'UTR clone - MiUTR3H-02864 from Creative biogene

Species Reactivities Human

DACH2 miRNA 3'UTR clone - MiUTR3H-02865 from Creative biogene

Species Reactivities Human

DACH2 miRNA 3'UTR clone - MiUTR3H-02866 from Creative biogene

Species Reactivities Human
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