KLHL41

Gene Symbol	KLHL41
Entrez Gene	10324
Alt Symbol	KBTBD10, Krp1, SARCOSIN
Species	Human
Gene Type	protein-coding
Description	kelch-like family member 41
Other Description	kel-like protein 23\|kelch repeat and BTB (POZ) domain containing 10\|kelch-like protein 41\|kelch-related protein 1\|sarcomeric muscle protein
Swissprots	Q53R42 O60662
Accessions	AAY24117 EAX11275 O60662 AA194290 AF056929 AAC13686 AF333387 AAG52886 AK316571 BAG38160 AY364252 AAQ76811 BC006534 AAH06534 DQ896002 ABM86980 EU176397 ABW03848 NM_006063 NP_006054
Function	Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. {ECO:0000250\|UniProtKB:A2AUC9}.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:19424503}. Cytoplasm, cytoskeleton {ECO:0000250\|UniProtKB:A2AUC9}. Cell projection, pseudopodium {ECO:0000250\|UniProtKB:Q9ER30}. Cell projection, ruffle {ECO:0000250\|UniProtKB:Q9ER30}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250\|UniProtKB:A2AUC9}. Sarcoplasmic reticulum membrane {ECO:0000269\|PubMed:24268659}. Endoplasmic reticulum membrane {ECO:0000269\|PubMed:24268659}. Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation- specific pseudopodia. {ECO:0000269\|PubMed:19424503}.
Tissue Specificity	Sarcomeric muscle.

KBTBD10 (E-13) - sc-132724 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

KBTBD10 (E-13): sc-132724. Western blot analysis of KBTBD10 expression in NCI-H292 whole cell lysate.

KBTBD10 (T-13) - sc-132725 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

KBTBD10 (D-25) - sc-101989 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

KBTBD10 (D-25): sc-101989. Western blot analysis of BTBD10 expression in human fetal muscle tissue extract.

Anti-KBTBD10 antibody - ab129446 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 antibody (ab129446) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, AP) - LS-C260819 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, APC) - LS-C260820 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, FITC) - LS-C260822 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, Biotin) - LS-C260821 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, Azide-free, HRP) - LS-C260823 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (C-Terminus) - LS-C31317 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa205-304) - LS-C308589 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-KBTBD10 / Sarcosin Antibody (aa546-575) - LS-C322362 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa547-575, PE) - LS-C260824 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (N-Terminus) - LS-C31318 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KBTBD10 / Sarcosin Antibody (aa213-262) - LS-C201292 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Human Fetal Muscle. KLHL41 antibody dilution 1.0 ug/ml.

Anti-KBTBD10 / Sarcosin Antibody (aa547-575) - LS-C165403 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

KBTBD10 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The KBTBD10 antibody detected the KBTBD10 protein (arrow).

KBTBD10 Antibody - NBP1-80310 from Novus Biologicals

Prices	$299.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: KBTBD10 Antibody [NBP1-80310] - Human Muscle lysate, concentration 1.25ug/ml.

KBTBD10 Antibody - NBP1-80787 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: KBTBD10 Antibody [NBP1-80787] - Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane & cytosol.

KBTBD10 Antibody - NBP1-80786 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: KBTBD10 Antibody [NBP1-80786] - Staining of human cell line A-431 shows positivity in nucleus, plasma membrane and cytoplasm.

KBTBD10 Antibody - NBP1-80788 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: KBTBD10 Antibody [NBP1-80788] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

KBTBD10 Antibody - H00010324-A01 from Novus Biologicals

Host	Mouse
Clonality	Polyclonal

KBTBD10 Antibody (1H3) - H00010324-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1H3

KBTBD10 Polyclonal Antibody - bs-8044R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KLHL41 antibody produced in rabbit - HPA021760 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-KBTBD10: <B>Cat. No. HPA021760</B>: Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Monoclonal Anti-KBTBD10 antibody produced in mouse - SAB1403059 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1H3

<B>Immunoblotting</B><BR/>Monoclonal Anti-KBTBD10: <B>Cat. No. SAB1403059</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.1 kDa using immunogen protein lysate.

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