Gene Symbol | KLHL41 |
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Entrez Gene | 10324 |
Alt Symbol | KBTBD10, Krp1, SARCOSIN |
Species | Human |
Gene Type | protein-coding |
Description | kelch-like family member 41 |
Other Description | kel-like protein 23|kelch repeat and BTB (POZ) domain containing 10|kelch-like protein 41|kelch-related protein 1|sarcomeric muscle protein |
Swissprots | Q53R42 O60662 |
Accessions | AAY24117 EAX11275 O60662 AA194290 AF056929 AAC13686 AF333387 AAG52886 AK316571 BAG38160 AY364252 AAQ76811 BC006534 AAH06534 DQ896002 ABM86980 EU176397 ABW03848 NM_006063 NP_006054 |
Function | Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. {ECO:0000250|UniProtKB:A2AUC9}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19424503}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A2AUC9}. Cell projection, pseudopodium {ECO:0000250|UniProtKB:Q9ER30}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9ER30}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:A2AUC9}. Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:24268659}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24268659}. Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation- specific pseudopodia. {ECO:0000269|PubMed:19424503}. |
Tissue Specificity | Sarcomeric muscle. |
Human KBTBD10 protein fragment - ab160945 from Abcam
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KBTBD10 / Sarcosin Antibody Blocking Peptide - LS-E4189 from LifeSpan Bioscience
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KBTBD10 / Sarcosin Antibody Blocking Peptide - LS-E13944 from LifeSpan Bioscience
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Recombinant Human KBTBD10 Protein - H00010324-Q01 from Novus Biologicals
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KBTBD10-Antibody-C-term-Blocking-Peptide - BP16445b from Abgent, a WuXi AppTec company
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KBTBD10 Blocking Peptide - 33R-1223 from Fitzgerald
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KBTBD10 Blocking Peptide - 33R-5874 from Fitzgerald
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KBTBD10 - H00010324-Q01-10 from Acris Antibodies
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KBTBD10 - H00010324-Q01-25 from Acris Antibodies
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KBTBD10 fusion protein - Ag22311 from Proteintech Group
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Recombinant Human Kelch repeat and BTB domain-containing protein 10(KBTBD10) - CSB-YP011995HU CSB-EP011995HU CSB-BP011995HU CSB-MP011995HU from Cusabio
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KBTBD10 - TP300295 from Acris Antibodies
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KBTBD10 Recombinant Protein Antigen - NBP1-80786PEP from Novus Biologicals
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KBTBD10 Recombinant Protein Antigen - NBP1-80788PEP from Novus Biologicals
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KBTBD10 Recombinant Protein Antigen - NBP1-80787PEP from Novus Biologicals
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KBTBD10 Peptide, Human - M34GP07907H from Creative Peptides
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Kelch repeat and BTB domain-containing protein 10 (KBTBD10), Recombinant Protein - MBS1011215 from MyBioSource
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