| Gene Symbol |
PRSS22
|
| Entrez Gene |
64063
|
| Alt Symbol |
BSSP-4, SP001LA, hBSSP-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protease, serine, 22
|
| Other Description |
brain-specific serine protease 4|prosemin|protease, serine S1 family member 22|serine protease 22|serine protease 26|tryptase epsilon
|
| Swissprots |
Q9GZN4 Q6UXE0 O43342
|
| Accessions |
AAB93671 EAW85456 Q9GZN4 AB010779 BAB20263 AF321182 AAG35070 AK309624 AK310904 AW083723 AY358396 AAQ88762 BC009726 AAH09726 BQ893064 HQ447842 ADQ32326 XM_005255473 XP_005255530 XM_006720915 XP_006720978 NM_022119 NP_071402
|
| Function |
Preferentially cleaves the synthetic substrate H-D-Leu- Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. {ECO:0000269|PubMed:11602603}.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:11602603}.
|
| Tissue Specificity |
Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland. {ECO:0000269|PubMed:11602603}.
|
