Gene Symbol | PRSS22 |
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Entrez Gene | 64063 |
Alt Symbol | BSSP-4, SP001LA, hBSSP-4 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 22 |
Other Description | brain-specific serine protease 4|prosemin|protease, serine S1 family member 22|serine protease 22|serine protease 26|tryptase epsilon |
Swissprots | Q9GZN4 Q6UXE0 O43342 |
Accessions | AAB93671 EAW85456 Q9GZN4 AB010779 BAB20263 AF321182 AAG35070 AK309624 AK310904 AW083723 AY358396 AAQ88762 BC009726 AAH09726 BQ893064 HQ447842 ADQ32326 XM_005255473 XP_005255530 XM_006720915 XP_006720978 NM_022119 NP_071402 |
Function | Preferentially cleaves the synthetic substrate H-D-Leu- Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. {ECO:0000269|PubMed:11602603}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:11602603}. |
Tissue Specificity | Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland. {ECO:0000269|PubMed:11602603}. |
Tryptase ε (H-55) - sc-98445 from Santa Cruz Biotechnology
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Tryptase ε (P-15) - sc-107313 from Santa Cruz Biotechnology
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Tryptase ε (S-13) - sc-107314 from Santa Cruz Biotechnology
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Anti-PRSS22 antibody - ab197158 from Abcam
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Anti-PRSS22 antibody - ab102077 from Abcam
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Anti-BSSP-4 / PRSS22 Antibody (aa33-306) - LS-C132711 from LifeSpan Bioscience
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Anti-BSSP-4 / PRSS22 Antibody (aa35-84) - LS-C116705 from LifeSpan Bioscience
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Anti-BSSP-4 / PRSS22 Antibody (aa33-306, Biotin) - LS-C126424 from LifeSpan Bioscience
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Tryptase epsilon/BSSP-4/PRSS22 Antibody (725445) - MAB5047 from Novus Biologicals
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Tryptase epsilon/BSSP-4/PRSS22 Antibody - NBP1-70688 from Novus Biologicals
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Tryptase epsilon/BSSP-4/PRSS22 Antibody - NBP2-13817 from Novus Biologicals
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Anti-PRSS22, (N-terminal) antibody produced in rabbit - SAB2106144 from Sigma-Aldrich
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Anti-PRSS22 antibody produced in rabbit - HPA049161 from Sigma-Aldrich
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PRSS22 antibody - N-terminal region (ARP57603_P050) - ARP57603_P050 from Aviva Systems Biology
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Mouse Tryptase epsilon /BSSP-4 Biotinylated Antibody - BAM20591 from R&D Systems
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Human Tryptase epsilon /BSSP-4 Antibody - MAB5047 from R&D Systems
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Human Tryptase epsilon/BSSP-4 MAb (Clone 725445), Mouse IgG2A - MAB5047-SP from R&D Systems
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Mouse Tryptase epsilon/BSSP-4 Biotinylated Antibody - BAF2059 from R&D Systems
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Mouse Tryptase epsilon/BSSP-4 Antibody - AF2059 from R&D Systems
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Mouse Tryptase epsilon/BSSP-4 Affinity Purified PAb, Goat IgG - AF2059-SP from R&D Systems
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Mouse Tryptase epsilon /BSSP-4 Antibody - MAB20592 from R&D Systems
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Mouse Tryptase epsilon/BSSP-4 MAb (Clone 246702), Rat IgG2A - MAB20592-SP from R&D Systems
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Mouse Tryptase epsilon /BSSP-4 Antibody - MAB2059 from R&D Systems
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Mouse Tryptase epsilon/BSSP-4 MAb (Clone 246744), Rat IgG2A - MAB2059-SP from R&D Systems
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PRSS22 antibody - 70R-3993 from Fitzgerald
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