PRSS22

Gene Symbol PRSS22
Entrez Gene 64063
Alt Symbol BSSP-4, SP001LA, hBSSP-4
Species Human
Gene Type protein-coding
Description protease, serine, 22
Other Description brain-specific serine protease 4|prosemin|protease, serine S1 family member 22|serine protease 22|serine protease 26|tryptase epsilon
Swissprots Q9GZN4 Q6UXE0 O43342
Accessions AAB93671 EAW85456 Q9GZN4 AB010779 BAB20263 AF321182 AAG35070 AK309624 AK310904 AW083723 AY358396 AAQ88762 BC009726 AAH09726 BQ893064 HQ447842 ADQ32326 XM_005255473 XP_005255530 XM_006720915 XP_006720978 NM_022119 NP_071402
Function Preferentially cleaves the synthetic substrate H-D-Leu- Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. {ECO:0000269|PubMed:11602603}.
Subcellular Location Secreted {ECO:0000269|PubMed:11602603}.
Tissue Specificity Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland. {ECO:0000269|PubMed:11602603}.

Tryptase ε (H-55) - sc-98445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tryptase ε (H-55): sc-98445. Western blot analysis of Tryptase ε expression in Mv 1 Lu whole cell lysate.

Tryptase ε (P-15) - sc-107313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Tryptase ε (P-15): sc-107313. Western blot analysis of Tryptase ε expression in Mv 1 Lu whole cell lysate.

Tryptase ε (S-13) - sc-107314 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Tryptase  (S-13): sc-107314. Western blot analysis of Tryptase  expression in TT whole cell lysate.

Anti-PRSS22 antibody - ab197158 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-PRSS22 antibody (ab197158) at 1/1000 dilution + Human fetal lung lysate

Anti-PRSS22 antibody - ab102077 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PRSS22 antibody (ab102077) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-BSSP-4 / PRSS22 Antibody (aa33-306) - LS-C132711 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µg
Host Rat
Clonality Monoclonal

Anti-BSSP-4 / PRSS22 Antibody (aa35-84) - LS-C116705 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRSS22 antibody LS-C116705 Western blot of HepG2 cell lysate.

Anti-BSSP-4 / PRSS22 Antibody (aa33-306, Biotin) - LS-C126424 from LifeSpan Bioscience

Prices $650.00
Sizes 250 µg
Host Rat
Clonality Monoclonal

Tryptase epsilon/BSSP-4/PRSS22 Antibody (725445) - MAB5047 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 725445

Tryptase epsilon/BSSP-4/PRSS22 Antibody - NBP1-70688 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Tryptase epsilon/BSSP-4/PRSS22 Antibody - NBP2-13817 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Tryptase epsilon/BSSP-4/PRSS22 Antibody [NBP2-13817] - Staining of human cell line CACO-2 shows localization to nucleoplasm.

Anti-PRSS22, (N-terminal) antibody produced in rabbit - SAB2106144 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PRSS22 (N-Terminal): <B>Cat. No. SAB2106144</B>: PRSS22 in HepG2 cell lysates with PRSS22 antibody at 1.0 μg/mL.

Anti-PRSS22 antibody produced in rabbit - HPA049161 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PRSS22:<B>Cat. No. HPA049161</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

PRSS22 antibody - N-terminal region (ARP57603_P050) - ARP57603_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Mouse Tryptase epsilon /BSSP-4 Biotinylated Antibody - BAM20591 from R&D Systems

Prices $389.00
Sizes 250 µg
Host Rat
Clone 246703

Human Tryptase epsilon /BSSP-4 Antibody - MAB5047 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 725445
Detection of Human Tryptase e/BSSP-4 by Western Blot. Western blot shows lysates of human pancreas tissue. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Tryptase e/BSSP-4 Monoclonal Antibody (Catalog # MAB5047) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). A specific band was detected for Tryptase e/BSSP-4 at approximately 34 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8 .

Human Tryptase epsilon/BSSP-4 MAb (Clone 725445), Mouse IgG2A - MAB5047-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 725445
Detection of Human Tryptase  epsilon/BSSP‑4 by Western Blot. Western blot shows lysates of human pancreas tissue. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Tryptase  epsilon/BSSP‑4 Monoclonal Antibody (Catalog # MAB5047) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Tryptase  epsilon/BSSP‑4 at approximately 34 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Mouse Tryptase epsilon/BSSP-4 Biotinylated Antibody - BAF2059 from R&D Systems

Prices $390.00
Sizes 50 µg
Host Goat

Mouse Tryptase epsilon/BSSP-4 Antibody - AF2059 from R&D Systems

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat

Mouse Tryptase epsilon/BSSP-4 Affinity Purified PAb, Goat IgG - AF2059-SP from R&D Systems

Host Goat
Clonality Polyclonal

Mouse Tryptase epsilon /BSSP-4 Antibody - MAB20592 from R&D Systems

Prices $99.00, $339.00
Sizes 25 µg, 500 µg
Host Rat
Clone 246702

Mouse Tryptase epsilon/BSSP-4 MAb (Clone 246702), Rat IgG2A - MAB20592-SP from R&D Systems

Host Rat
Clonality Monoclonal
Clone 246702

Mouse Tryptase epsilon /BSSP-4 Antibody - MAB2059 from R&D Systems

Prices $99.00, $339.00
Sizes 25 µg, 500 µg
Host Rat
Clone 246744

Mouse Tryptase epsilon/BSSP-4 MAb (Clone 246744), Rat IgG2A - MAB2059-SP from R&D Systems

Host Rat
Clonality Monoclonal
Clone 246744

PRSS22 antibody - 70R-3993 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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