Gene Symbol | PRSS22 |
---|---|
Entrez Gene | 64063 |
Alt Symbol | BSSP-4, SP001LA, hBSSP-4 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 22 |
Other Description | brain-specific serine protease 4|prosemin|protease, serine S1 family member 22|serine protease 22|serine protease 26|tryptase epsilon |
Swissprots | Q9GZN4 Q6UXE0 O43342 |
Accessions | AAB93671 EAW85456 Q9GZN4 AB010779 BAB20263 AF321182 AAG35070 AK309624 AK310904 AW083723 AY358396 AAQ88762 BC009726 AAH09726 BQ893064 HQ447842 ADQ32326 XM_005255473 XP_005255530 XM_006720915 XP_006720978 NM_022119 NP_071402 |
Function | Preferentially cleaves the synthetic substrate H-D-Leu- Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. {ECO:0000269|PubMed:11602603}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:11602603}. |
Tissue Specificity | Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland. {ECO:0000269|PubMed:11602603}. |