AGTRAP

Gene Symbol	AGTRAP
Entrez Gene	57085
Alt Symbol	ATRAP
Species	Human
Gene Type	protein-coding
Description	angiotensin II receptor-associated protein
Other Description	AT1 receptor-associated protein|ATI receptor-associated protein|angiotensin II, type I receptor-associated protein|type-1 angiotensin II receptor-associated protein
Swissprots	Q5SNV5 A8MVQ5 Q9NRW9 Q5SNV4 Q6RW13 Q96PL4 Q96AC0
Accessions	AAR25556 EAW71702 EAW71703 EAW71704 EAW71705 Q6RW13 AF165187 AAF89547 AF312374 AAL26806 AI741916 AK290042 BAF82731 BC011946 BC017328 AAH17328 BE782705 BI117521 BQ672962 CA866314 CD674964 DQ892619 ABM83545 DQ895859 ABM86785 XM_011541799 XP_011540101 XM_011541800 XP_011540102 XM_011541801 XP_011540103 XM_011541802 XP_011540104 XM_011541803 XP_011540105 NM_001040194 NP_001035284 NM_001040195 NP_001035285 NM_001040196 NP_001035286 NM_001040197 NP_001035287 NM_020350 NP_065083
Function	Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. {ECO:0000269|PubMed:12960423}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Golgi apparatus membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Tissue Specificity	Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. {ECO:0000269|PubMed:11733189}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AGTRAP full length protein - ab163472 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AGTRAP protein fragment - ab163473 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

AGTRAP / ATRAP Antibody Blocking Peptide - LS-E5884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AGTRAP Protein - H00057085-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AGTRAP Partial Recombinant Protein - H00057085-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AGTRAP-Antibody-C-term-Blocking-Peptide - BP18437b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AGTRAP / ATRAP - H00057085-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AGTRAP / ATRAP - H00057085-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AGTRAP / ATRAP - H00057085-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AGTRAP / ATRAP - H00057085-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AGTRAP fusion protein - Ag2116 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human AGTRAP, GST-tagged - AGTRAP-9486H from Creative Biomart Category Protein Source E.coli Species Human

AGTRAP Recombinant Protein Antigen - NBP1-91654PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

AGTRAP Peptide, Human - M34GP00392H from Creative Peptides Category Peptide Source Synthetic. Species Human

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