AGTRAP

Gene Symbol AGTRAP
Entrez Gene 57085
Alt Symbol ATRAP
Species Human
Gene Type protein-coding
Description angiotensin II receptor-associated protein
Other Description AT1 receptor-associated protein|ATI receptor-associated protein|angiotensin II, type I receptor-associated protein|type-1 angiotensin II receptor-associated protein
Swissprots Q5SNV5 A8MVQ5 Q9NRW9 Q5SNV4 Q6RW13 Q96PL4 Q96AC0
Accessions AAR25556 EAW71702 EAW71703 EAW71704 EAW71705 Q6RW13 AF165187 AAF89547 AF312374 AAL26806 AI741916 AK290042 BAF82731 BC011946 BC017328 AAH17328 BE782705 BI117521 BQ672962 CA866314 CD674964 DQ892619 ABM83545 DQ895859 ABM86785 XM_011541799 XP_011540101 XM_011541800 XP_011540102 XM_011541801 XP_011540103 XM_011541802 XP_011540104 XM_011541803 XP_011540105 NM_001040194 NP_001035284 NM_001040195 NP_001035285 NM_001040196 NP_001035286 NM_001040197 NP_001035287 NM_020350 NP_065083
Function Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. {ECO:0000269|PubMed:12960423}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Golgi apparatus membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Tissue Specificity Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. {ECO:0000269|PubMed:11733189}.

AGTRAP CRISPR/Cas9 KO Plasmid (h) - sc-410057 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP HDR Plasmid (h) - sc-410057-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP Double Nickase Plasmid (h) - sc-410057-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP Double Nickase Plasmid (h2) - sc-410057-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP CRISPR Activation Plasmid (h) - sc-410057-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP CRISPR Activation Plasmid (h2) - sc-410057-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP Lentiviral Activation Particles (h) - sc-410057-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP Lentiviral Activation Particles (h2) - sc-410057-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGTRAP siRNA (h) - sc-78862 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGTRAP shRNA Plasmid (h) - sc-78862-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGTRAP shRNA (h) Lentiviral Particles - sc-78862-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGTRAP RNAi - H00057085-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: AGTRAP RNAi [H00057085-R01V] - Analysis of AGTRAP over-expressed 293 cell line. Lane 2 cotransfected with AGTRAP Validated Chimera RNAi Lane 1 non-transfected control. Blot probed with H00057085-M02. GAPDH (36.1 kDa) used as loading control.

AGTRAP RNAi - H00057085-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015501 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1153 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1152 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1153 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1152 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05509 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05509

AGTRAP siRNA (Human) - CRJ1310 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGTRAP - MBS8209836 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AGTRAP (NM_020350.4) - SHH233542 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AGTRAP(NM_020350.4) - SHG046407 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AGTRAP(NM_001040196.1) - SHG046483 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AGTRAP(NM_020350.4) - SHG046505 from Creative biogene

Category siRNA
Species Reactivities Human
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