Gene Symbol | AGTRAP |
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Entrez Gene | 57085 |
Alt Symbol | ATRAP |
Species | Human |
Gene Type | protein-coding |
Description | angiotensin II receptor-associated protein |
Other Description | AT1 receptor-associated protein|ATI receptor-associated protein|angiotensin II, type I receptor-associated protein|type-1 angiotensin II receptor-associated protein |
Swissprots | Q5SNV5 A8MVQ5 Q9NRW9 Q5SNV4 Q6RW13 Q96PL4 Q96AC0 |
Accessions | AAR25556 EAW71702 EAW71703 EAW71704 EAW71705 Q6RW13 AF165187 AAF89547 AF312374 AAL26806 AI741916 AK290042 BAF82731 BC011946 BC017328 AAH17328 BE782705 BI117521 BQ672962 CA866314 CD674964 DQ892619 ABM83545 DQ895859 ABM86785 XM_011541799 XP_011540101 XM_011541800 XP_011540102 XM_011541801 XP_011540103 XM_011541802 XP_011540104 XM_011541803 XP_011540105 NM_001040194 NP_001035284 NM_001040195 NP_001035285 NM_001040196 NP_001035286 NM_001040197 NP_001035287 NM_020350 NP_065083 |
Function | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. {ECO:0000269|PubMed:12960423}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Golgi apparatus membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles. |
Tissue Specificity | Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. {ECO:0000269|PubMed:11733189}. |
AGTRAP (FL-159) - sc-134652 from Santa Cruz Biotechnology
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AGTRAP (F-6) - sc-271367 from Santa Cruz Biotechnology
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AGTRAP (S-14) - sc-162504 from Santa Cruz Biotechnology
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Anti-AGTRAP antibody - ab197790 from Abcam
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Anti-AGTRAP antibody - ab89247 from Abcam
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Anti-AGTRAP antibody - ab85175 from Abcam
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Anti-AGTRAP antibody - ab172736 from Abcam
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Anti-AGTRAP antibody - ab57555 from Abcam
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Anti-AGTRAP / ATRAP Antibody (aa133-159, AP) - LS-C251041 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159, Biotin) - LS-C251043 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159, APC) - LS-C251042 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159, FITC) - LS-C251044 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159, PE) - LS-C251047 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159, Azide-free, HRP) - LS-C251046 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody - LS-C306141 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (C-Terminus) - LS-C137123 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa108-210) - LS-C306142 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody - LS-C309359 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody - LS-C309358 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa132-159) - LS-C319380 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (aa133-159) - LS-C161023 from LifeSpan Bioscience
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Anti-AGTRAP / ATRAP Antibody (clone 1G2) IHC-plus⢠- LS-B9942 from LifeSpan Bioscience
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AGTRAP Antibody (1G2) - H00057085-M02 from Novus Biologicals
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AGTRAP Antibody - NBP1-91654 from Novus Biologicals
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AGTRAP Antibody - H00057085-B01P from Novus Biologicals
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