CCL8

Gene Symbol CCL8
Entrez Gene 6355
Alt Symbol HC14, MCP-2, MCP2, SCYA10, SCYA8
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 8
Other Description C-C motif chemokine 8|monocyte chemoattractant protein 2|monocyte chemotactic protein 2|small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)|small-inducible cytokine A8
Swissprots P78388 P80075 A0AV77
Accessions CAA68168 EAW80207 EAW80208 P80075 BC126242 AAI26243 HQ258700 ADR83451 Y10802 CAA71760 Y16645 CAA76341 NM_005623 NP_005614
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. {ECO:0000269|PubMed:9558113}.
Subcellular Location Secreted.
Tissue Specificity Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

MCP-2 CRISPR/Cas9 KO Plasmid (h) - sc-416777 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 HDR Plasmid (h) - sc-416777-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 Double Nickase Plasmid (h) - sc-416777-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 Double Nickase Plasmid (h2) - sc-416777-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 CRISPR Activation Plasmid (h) - sc-416777-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 CRISPR Activation Plasmid (h2) - sc-416777-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 Lentiviral Activation Particles (h) - sc-416777-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 Lentiviral Activation Particles (h2) - sc-416777-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCP-2 siRNA (h) - sc-43915 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCP-2 shRNA Plasmid (h) - sc-43915-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCP-2 shRNA (h) Lentiviral Particles - sc-43915-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU119591 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5623 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5623 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CCL8 siRNA (Human) - CRH4288 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCL8 - MBS8240566 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCL8 (NM_005623.2) - SHH257729 from Creative biogene

Category siRNA
Species Reactivities Human

CCL8 shRNA Plasmid (Human) - CHH4288 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCL8 miRNA 3'UTR clone - MiUTR1H-01810 from Creative biogene

Species Reactivities Human
Search more