CCL8

Gene Symbol	CCL8
Entrez Gene	6355
Alt Symbol	HC14, MCP-2, MCP2, SCYA10, SCYA8
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 8
Other Description	C-C motif chemokine 8|monocyte chemoattractant protein 2|monocyte chemotactic protein 2|small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)|small-inducible cytokine A8
Swissprots	P78388 P80075 A0AV77
Accessions	CAA68168 EAW80207 EAW80208 P80075 BC126242 AAI26243 HQ258700 ADR83451 Y10802 CAA71760 Y16645 CAA76341 NM_005623 NP_005614
Function	Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. {ECO:0000269|PubMed:9558113}.
Subcellular Location	Secreted.
Tissue Specificity	Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MCP2 full length protein - ab9672 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli Species Human

Active human MCP2 full length protein - ab191751 from Abcam Category Protein Prices $192.00 Sizes 25 µg Source E. coli Species Human

Active human MCP2 full length protein - ab73834 from Abcam Category Protein Prices $200.00 Sizes 10 µg Source E. coli Species Human

Active mouse MCP2 full length protein - ab192109 from Abcam Category Protein Prices $192.00 Sizes 20 µg Source E. coli Species Mouse

Active mouse MCP2 full length protein - ab56732 from Abcam Category Protein Prices $315.00 Sizes 20 µg Source E. coli Species Mouse

Active mouse MCP2 protein fragment - ab202815 from Abcam Category Protein Prices $359.00 Sizes 5 µg Source E. coli Species Mouse

Human MCP2 full length protein - ab151887 from Abcam Category Protein Source E. coli Species Human

Human MCP2 full length protein - ab176075 from Abcam Category Protein Source Synthetic Species Human

Human MCP2 protein fragment - ab175171 from Abcam Category Protein Source Synthetic Species Human

Recombinant Human CCL8/MCP-2 Protein - NBP2-34969 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

CCL8/MCP-2 Recombinant Protein - P4423 from Novus Biologicals Category Protein Prices $549.00 Sizes 10 µg Species Human

Recombinant Human CCL8/MCP-2 Protein - NBP1-99400 from Novus Biologicals Category Protein Prices $190.00 Sizes 10 µg Source E. coli Species Human

MCP2 protein - GTX29672 from GeneTex Category Protein Prices $299.00 Sizes 10 μg Species Human

MCP2 recombinant protein (Active) - GTX65240 from GeneTex Category Protein Prices $249.00 Sizes 10 μg Source E. coli Species Human

MCP2 Recombinant Protein (Active) - GTX48373-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

Recombinant Human CCL8/MCP-2 - 281-CP-010 from R&D Systems Category Protein Source E. coli-derived, Gln24-Pro99

Recombinant Human CCL8/MCP-2 - 281-CP-050 from R&D Systems Category Protein Source E. coli-derived, Gln24-Pro99

Recombinant Human CCL8/MCP-2, CF - 281-CP-010/CF from R&D Systems Category Protein Source E. coli-derived, Gln24-Pro99

Recombinant Human CCL8/MCP-2, CF - 281-CP-050/CF from R&D Systems Category Protein Source E. coli-derived, Gln24-Pro99

MCP 2 Protein (OPPA00415) - OPPA00415 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Recombinant MCP-2 / CCL8 (OPSD00067) - OPSD00067 from Aviva Systems Biology Category Protein Prices $105.00 Sizes 2 µg

Recombinant MCP-2 / CCL8 (OPSD00149) - OPSD00149 from Aviva Systems Biology Category Protein Prices $105.00 Sizes 2 µg

Human CCL8 protein - orb245781 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

CCL8 protein - orb197643 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human MCP 2 protein - orb168794 from Biorbyt Category Protein Prices $187.00, $323.00 Sizes 2 μg, 10 μg Species Human, Mouse, Rat, Monkey, Hamster

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