PTPN13

Gene Symbol PTPN13
Entrez Gene 5783
Alt Symbol FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
Other Description fas-associated protein-tyrosine phosphatase 1|hPTPE1|protein-tyrosine phosphatase 1E|protein-tyrosine phosphatase PTPL1|tyrosine-protein phosphatase non-receptor type 13
Swissprots Q9UDA8 Q15264 Q8IWH7 Q15263 Q9NYN9 Q12923 Q15674 Q16826 Q15159 B2RTR0 Q15265
Accessions AAY40972 CCA94573 EAX05965 EAX05966 EAX05967 EAX05968 Q12923 AB208904 BAD92141 AF233323 AAF63474 AK056151 BC039610 AAH39610 BC139915 BC140777 AAI40778 BC144520 BG202767 BX647553 CAH10380 D21209 BAA04750 D21210 BAA04751 D21211 BAA04752 DA625835 L34583 AAC41755 U12128 AAB60339 U12129 U12130 U12131 U12132 X79676 CAA56124 X80289 CAA56563 XM_005263167 XP_005263224 XM_011532163 XP_011530465 XM_011532164 XP_011530466 XM_011532165 XP_011530467 XM_011532166 XP_011530468 XM_011532167 XP_011530469 XM_011532168 XP_011530470 XM_011532169 XP_011530471 XM_011532170 XP_011530472 XM_011532171 XP_011530473 XM_011532172 XP_011530474 NM_006264 NP_006255 NM_080683 NP_542414 NM_080684 NP_542415 NM_080685 NP_542416
Function Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317). {ECO:0000269|PubMed:15611135, ECO:0000269|PubMed:23604317}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:11356191}. Cell projection, lamellipodium {ECO:0000269|PubMed:11356191}. Note=Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover.
Tissue Specificity Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.

Active human PTPN13 protein fragment - ab42581 from Abcam

Category Protein
Prices $232.00
Sizes 20 µg
Source E. coli
Species Human

Human PTPN13 peptide - ab17701 from Abcam

Category Peptide
All lanes : Anti-PTPN13 antibody ( ab10867 ) at 2 µg/ml Lane 1 : 0.1µg recombinant PTP-BAS (PTPN13) Lane 2 : 0.1µg recombinant PTPH1 (PTPN3) Lane 3 : 0.1µg recombinant STEP (PTPN5) Lane 4 : 0.1µg recombinant SHP2 (PTPN11) Lane 5 : 0.1µg recombinant BDP1 (PTPN18) Performed under reducing conditions. Predicted band size : 277 kDa Observed band size : 58 kDa ( why is the actual band size different from the predicted? ) Recombinant PTP phosphatase domains (0.1 µg/lane) were probed with ab10867 at 2ug/ml. The antibody recognises PTP-BAS (PTPN13) GST fusion protein at ~58kDa. Recombinant PTP phosphatase domains provided by PurelyProteins

Recombinant Human PTPN13/PTPL1 Protein - H00005783-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PTPN13 - H00005783-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PTPN13 - H00005783-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human PTPN13,GST-tagged,Active - PTPN13-463H from Creative Biomart

Category Protein
Source E.coli.

Recombinant Human Tyrosine-protein phosphatase non-receptor type 13(PTPN13) ,par - CSB-YP614263HU CSB-EP614263HU CSB-BP614263HU CSB-MP614263HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 13 (PTPN13) - RPD593Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 13 (PTPN13) - RPD593Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 13 (PTPN13) - RPD593Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

PTPN13-Antibody-C-term-Blocking-Peptide - BP8423a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PTPN13 Peptide, Human - M34GP12697H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PTPN13 fusion protein - Ag26236 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PTPN13 Recombinant Protein (OPCD00396) - OPCD00396 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human
Search more