ESYT2

Gene Symbol ESYT2
Entrez Gene 57488
Alt Symbol CHR2SYT, E-Syt2, FAM62B
Species Human
Gene Type protein-coding
Description extended synaptotagmin-like protein 2
Other Description chr2 synaptotagmin|extended synaptotagmin-2|family with sequence similarity 62 (C2 domain containing), member B
Swissprots Q9BQS0 Q6UKI4 A4D229 Q9ULJ2 A0FGR8 Q6ZTU0 Q6ZVU1 Q9NW47 Q69YJ2
Accessions A0FGR8 EAL23931 EAX04590 EAX04591 AB033054 BAA86542 AJ303365 CAC33887 AK001181 BAA91539 AK026710 AK056953 AK124091 BAC85769 AK126214 BAC86489 AK308824 AL833233 CAH10642 AY368150 AAR89381 BC013957 AAH13957 BC152806 AAI52807 DQ993201 ABJ97706 NM_020728 NP_065779
Function Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. {ECO:0000269|PubMed:17360437, ECO:0000269|PubMed:20833364, ECO:0000269|PubMed:23791178, ECO:0000269|PubMed:24847877}.
Subcellular Location Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Detected at sites of contact between the endoplasmic reticulum membrane and the cell membrane. Recruited to the cell membrane via the third C2 domain.
Tissue Specificity Widely expressed with high level in cerebellum. {ECO:0000269|PubMed:17360437}.

FAM62B CRISPR/Cas9 KO Plasmid (h) - sc-412811 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B HDR Plasmid (h) - sc-412811-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B Double Nickase Plasmid (h) - sc-412811-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B Double Nickase Plasmid (h2) - sc-412811-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B CRISPR Activation Plasmid (h) - sc-412811-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B CRISPR Activation Plasmid (h2) - sc-412811-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B Lentiviral Activation Particles (h) - sc-412811-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B Lentiviral Activation Particles (h2) - sc-412811-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM62B siRNA (h) - sc-89470 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM62B shRNA Plasmid (h) - sc-89470-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM62B shRNA (h) Lentiviral Particles - sc-89470-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM62B RNAi - H00057488-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU054041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7997 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

ESYT2 siRNA (Human) - CRJ1478 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ESYT2 - MBS8207124 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ESYT2 (NM_020728.2) - SHH287505 from Creative biogene

Category siRNA
Species Reactivities Human

ESYT2 shRNA Plasmid (Human) - CHJ1478 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ESYT2 miRNA 3'UTR clone - MiUTR4H-TG03176 from Creative biogene

Species Reactivities Human
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