ESYT2

Gene Symbol ESYT2
Entrez Gene 57488
Alt Symbol CHR2SYT, E-Syt2, FAM62B
Species Human
Gene Type protein-coding
Description extended synaptotagmin-like protein 2
Other Description chr2 synaptotagmin|extended synaptotagmin-2|family with sequence similarity 62 (C2 domain containing), member B
Swissprots Q9BQS0 Q6UKI4 A4D229 Q9ULJ2 A0FGR8 Q6ZTU0 Q6ZVU1 Q9NW47 Q69YJ2
Accessions A0FGR8 EAL23931 EAX04590 EAX04591 AB033054 BAA86542 AJ303365 CAC33887 AK001181 BAA91539 AK026710 AK056953 AK124091 BAC85769 AK126214 BAC86489 AK308824 AL833233 CAH10642 AY368150 AAR89381 BC013957 AAH13957 BC152806 AAI52807 DQ993201 ABJ97706 NM_020728 NP_065779
Function Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. {ECO:0000269|PubMed:17360437, ECO:0000269|PubMed:20833364, ECO:0000269|PubMed:23791178, ECO:0000269|PubMed:24847877}.
Subcellular Location Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Detected at sites of contact between the endoplasmic reticulum membrane and the cell membrane. Recruited to the cell membrane via the third C2 domain.
Tissue Specificity Widely expressed with high level in cerebellum. {ECO:0000269|PubMed:17360437}.

FAM62B (V-12) - sc-162803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FAM62B antibody - ab88900 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-FAM62B antibody (ab88900) at 1/500 dilution + human colon tissue lysate at 50 µg

Anti-FAM62B antibody - ab57455 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57455 FAM62B antibody at 1ug/ml.

Anti-FAM62B antibody - ab98049 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FAM62B antibody (ab98049) at 1 µg/ml (in 5% skim milk / PBS buffer) + HT1080 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-FAM62B antibody [1E10] - ab178514 from Abcam

Prices $407.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E10
Immunohistochemical analysis of FAM62B expression in paraffin embedded, formalin fixed Human breast epithelium tissue using ab178514 at 10 µg/ml.

Anti-ESYT2 / E-Syt2 Antibody (aa611-660) - LS-C107690 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ESYT2 antibody LS-C107690 Western blot of HT1080 cell lysate.

Anti-ESYT2 / E-Syt2 Antibody (clone 1E10) IHC-plus™ - LS-B8988 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E10
Anti-ESYT2 / E-Syt2 antibody IHC staining of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FAM62B Antibody - NBP1-85627 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAM62B Antibody [NBP1-85627] - Analysis in human cell line SK-BR-3.

FAM62B Antibody - NBP1-59988 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAM62B Antibody [NBP1-59988] - HT1080 cell lysate, concentration 0.2-1 ug/ml.

FAM62B Antibody (4C3) - H00057488-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C3

FAM62B Antibody (1E10) - H00057488-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E10

FAM62B Antibody - H00057488-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody - bs-11003R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11003R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11003R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11003R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11003R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, Cy3 Conjugated - bs-11003R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, Cy5 Conjugated - bs-11003R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, Cy5.5 Conjugated - bs-11003R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, Cy7 Conjugated - bs-11003R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, FITC Conjugated - bs-11003R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, Biotin Conjugated - bs-11003R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ESYT2/FAM62B Polyclonal Antibody, HRP Conjugated - bs-11003R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-FAM62B antibody produced in mouse - WH0057488M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C3
<B>Immunoblotting</B><BR/>Monoclonal Anti-FAM62B, <B>Cat. No. WH0057488M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~65.49 kDa using immunogen protein lysate.
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