UBE2Z

Gene Symbol UBE2Z
Entrez Gene 65264
Alt Symbol HOYS7, USE1
Species Human
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2Z
Other Description UBA6-specific enzyme E2|uba6-specific E2 conjugating enzyme 1|ubiquitin carrier protein Z|ubiquitin-conjugating enzyme E2 Z|ubiquitin-protein ligase Z
Swissprots A6NC60 Q9H832 Q8TCM4 Q7L354 Q9H893 A6N8M6
Accessions EAW94701 EAW94702 EAW94703 EAW94704 Q9H832 AA843379 AA845421 AB025426 BAB87810 AK023917 BAB14724 AK024030 BAB14789 AK091644 AK122770 AK130303 AK296865 BAG59428 AL713782 CAD28542 BC015169 AAH15169 BC015890 AAH15890 CR457322 CAG33603 DA928380 EF623992 ABR25252 NM_023079 NP_075567
Function Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. {ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000269|PubMed:17464193, ECO:0000269|PubMed:17597759}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17160626}. Nucleus {ECO:0000269|PubMed:17160626}.
Tissue Specificity Widely expressed. Highly in placenta, pancreas, spleen and testis. {ECO:0000269|PubMed:17160626, ECO:0000269|PubMed:17597759}.
Top Pathways Ubiquitin mediated proteolysis

Anti-UBE2Z antibody - ab195795 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z antibody - ab130621 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UBE2Z antibody (ab130621) at 1/100 dilution + MDA-MB453 cell line lysate at 35 µg

Anti-UBE2Z antibody - ab68001 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-UBE2Z antibody (ab68001) at 1/500 dilutionLane 1 : UBE2Z transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-UBE2Z antibody - ab123036 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-UBE2Z antibody (ab123036) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-UBE2Z / USE1 Antibody (aa284-310, AP) - LS-C272939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa284-310, APC) - LS-C272940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa284-310, Biotin) - LS-C272941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa284-310, FITC) - LS-C272942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa284-310, PE) - LS-C272944 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa283-310) - LS-C326146 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (aa284-310, Azide-free, HRP) - LS-C272943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody - LS-C343772 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody (C-Terminus) - LS-C146022 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UBE2Z antibody LS-C146022 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-UBE2Z / USE1 Antibody (aa284-310) - LS-C157314 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UBE2Z Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The UBE2Z antibody detected the UBE2Z protein (arrow).

Anti-UBE2Z / USE1 Antibody (aa208-257) - LS-C170394 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UBE2Z / USE1 Antibody - LS-C346400 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using UBE2Z antibody. Blue: DAPI for nuclear staining.

UBE2Z Antibody - NBP1-82245 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBE2Z Antibody [NBP1-82245] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

Use1/UBE2Z Antibody [Unconjugated] - AF8154 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

UBE2Z Antibody (4B1) - H00065264-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B1

UBE2Z Antibody - H00065264-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: UBE2Z Antibody [H00065264-B01P] - Analysis of UBE2Z expression in transfected 293T cell line by UBE2Z polyclonal antibody. Lane 1: UBE2Z transfected lysate(27.06 KDa). Lane 2: Non-transfected lysate.

Monoclonal Anti-UBE2Z antibody produced in mouse - SAB1409673 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B1
<B>Immunoblotting</B><BR/>Monoclonal Anti-UBE2Z: <B>Cat. No. SAB1409673</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~38.2 kDa using K-562 lysate.

Anti-UBE2Z antibody produced in mouse - SAB1407918 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UBE2Z: <B>Cat. No. SAB1407918</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~27.1 kDa using UBE2Z transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-UBE2Z antibody produced in rabbit - HPA007922 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBE2Z: <B>Cat. No. HPA007922</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis shows strong nuclear and cytoplasmic positivity positivity in cells in seminiferous ducts and moderate in Leydig cells).

Anti-UBE2Z (171-185) antibody produced in rabbit - U3634 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-UBE2Z (171-185): <B>Cat. No. U3634</B>: Immunofluorescence of HUVEC cells using UBE2Z (171-185) (RB),<B>Cat. No. U3634</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-UBE2Z (216-230) antibody produced in rabbit - U3759 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-UBE2Z (216-230), <B>Cat. No. U3759</B>: Immunofluorescence of HUVEC cells using Anti-UBE2Z (216-230), U3759 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com
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