Gene Symbol | UBE2Z |
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Entrez Gene | 65264 |
Alt Symbol | HOYS7, USE1 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2Z |
Other Description | UBA6-specific enzyme E2|uba6-specific E2 conjugating enzyme 1|ubiquitin carrier protein Z|ubiquitin-conjugating enzyme E2 Z|ubiquitin-protein ligase Z |
Swissprots | A6NC60 Q9H832 Q8TCM4 Q7L354 Q9H893 A6N8M6 |
Accessions | EAW94701 EAW94702 EAW94703 EAW94704 Q9H832 AA843379 AA845421 AB025426 BAB87810 AK023917 BAB14724 AK024030 BAB14789 AK091644 AK122770 AK130303 AK296865 BAG59428 AL713782 CAD28542 BC015169 AAH15169 BC015890 AAH15890 CR457322 CAG33603 DA928380 EF623992 ABR25252 NM_023079 NP_075567 |
Function | Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. {ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000269|PubMed:17464193, ECO:0000269|PubMed:17597759}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17160626}. Nucleus {ECO:0000269|PubMed:17160626}. |
Tissue Specificity | Widely expressed. Highly in placenta, pancreas, spleen and testis. {ECO:0000269|PubMed:17160626, ECO:0000269|PubMed:17597759}. |
Top Pathways | Ubiquitin mediated proteolysis |
Human UBE2Z full length protein - ab163929 from Abcam
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Human UBE2Z full length protein - ab173055 from Abcam
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Human UBE2Z protein fragment - ab167938 from Abcam
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Human UBE2Z protein fragment - ab163930 from Abcam
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UBE2Z / USE1 Antibody Blocking Peptide - LS-E4846 from LifeSpan Bioscience
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UBE2Z / USE1 Antibody Blocking Peptide - LS-E22963 from LifeSpan Bioscience
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UBE2Z / USE1 Antibody Blocking Peptide - LS-E22964 from LifeSpan Bioscience
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UBE2Z Recombinant Protein - H00065264-P01 from Novus Biologicals
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UBE2Z Partial Recombinant Protein - H00065264-Q01 from Novus Biologicals
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UBE2Z-Antibody-C-term-Blocking-Peptide - BP17226b from Abgent, a WuXi AppTec company
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Recombinant Human His6-Use1/UBE2Z, CF - E2-677-050 from R&D Systems
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Recombinant Human His6-Use1/UBE2Z, CF - E2-677-100 from R&D Systems
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Human UBE2Z protein - orb163548 from Biorbyt
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UBE2Z protein (His tag) - 80R-3859 from Fitzgerald
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UBE2Z (1-246, His-tag) - AR51546PU-N from Acris Antibodies
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UBE2Z (1-246, His-tag) - AR51546PU-S from Acris Antibodies
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UBE2Z - H00065264-P01-10 from Acris Antibodies
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UBE2Z - H00065264-P01-25 from Acris Antibodies
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UBE2Z - H00065264-Q01-10 from Acris Antibodies
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UBE2Z - H00065264-Q01-25 from Acris Antibodies
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UBE2Z, 1-246aa, Human, His tag, E.coli - 01-P2726 from ARP American Research Products
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UBE2Z, Human, Recombinant - 19-CG35 from ARP American Research Products
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UBE2Z fusion protein - Ag10347 from Proteintech Group
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UBE2Z fusion protein - Ag10469 from Proteintech Group
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Recombinant Human UBE2Z Enzyme - BP002648-CG35 from Syd Labs
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