CD47

Gene Symbol	CD47
Entrez Gene	961
Alt Symbol	IAP, MER6, OA3
Species	Human
Gene Type	protein-coding
Description	CD47 molecule
Other Description	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)|CD47 glycoprotein|Rh-related antigen|antigen identified by monoclonal antibody 1D8|antigenic surface determinant protein OA3|integrin associated protein|integrin-associated protein|integrin-associated signal transducer|leukocyte surface antigen CD47
Swissprots	D3DN59 Q08722 Q53Y71 Q96A60 A8K198
Accessions	AAQ11189 EAW79732 EAW79733 EAW79734 Q08722 AI701980 AK096670 AK124152 AK289813 BAF82502 AL832675 BC010016 AAH10016 BC012884 AAH12884 BC037306 AAH37306 BC042889 BC045593 BC053959 BI753986 BT006907 AAP35553 BX640889 CB995865 DQ890756 ABM81682 DQ891811 ABM82737 DQ893920 ABM84846 LN680437 CEJ95640 X69398 CAA49196 Z25521 CAA80977 XM_005247908 XP_005247965 XM_005247909 XP_005247966 XR_241521 XR_241522 XR_924218 XR_924219 XR_924220 NM_001777 NP_001768 NM_198793 NP_942088 NM_001025079 NM_001025080
Function	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. {ECO:0000250, ECO:0000269|PubMed:11509594, ECO:0000269|PubMed:15383453, ECO:0000269|PubMed:7691831}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:7691831}; Multi-pass membrane protein {ECO:0000269|PubMed:7691831}.
Tissue Specificity	Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.
Top Pathways	ECM-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD47 293T Cell Transient Overexpression Lysate(Denatured) - H00000961-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CD47 overexpression lysate - LY404792 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD47 overexpression lysate - LY419754 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD47 overexpression lysate - LY430763 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD47 293 Cell Lysate - 403444 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CD47 293 Cell Lysate - 409252 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CD47 Overexpression Lysate (Denatured) - H00000961-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

CD47 Overexpression Lysate (Native) - NBL1-08954 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD47 (h): 293 Lysate - sc-112975 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CD47 Over-expression Lysate Product - GWB-A718E3 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

CD47 Over-expression Lysate Product - GWB-76935A from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human CD47 HEK293 Cell Lysate (WB positive control) - 12283-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

CD47 Overexpression Lysate (Native) - NBP2-10084 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD47 Overexpression Lysate (Denatured) - H00000961-T04 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human CD47 Human Cells Transfected Lysate (positive control) (denatured) - orb174798 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human CD47 Knockdown Stable Cell Line - CSC-DC002754 from Creative biogene Category Cell Line Species Human

CD47 KO Cell Lysate-HEK293T - CLKO-0976 from Creative biogene Category Cell Lysate

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