CD47

Gene Symbol	CD47
Entrez Gene	961
Alt Symbol	IAP, MER6, OA3
Species	Human
Gene Type	protein-coding
Description	CD47 molecule
Other Description	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)|CD47 glycoprotein|Rh-related antigen|antigen identified by monoclonal antibody 1D8|antigenic surface determinant protein OA3|integrin associated protein|integrin-associated protein|integrin-associated signal transducer|leukocyte surface antigen CD47
Swissprots	D3DN59 Q08722 Q53Y71 Q96A60 A8K198
Accessions	AAQ11189 EAW79732 EAW79733 EAW79734 Q08722 AI701980 AK096670 AK124152 AK289813 BAF82502 AL832675 BC010016 AAH10016 BC012884 AAH12884 BC037306 AAH37306 BC042889 BC045593 BC053959 BI753986 BT006907 AAP35553 BX640889 CB995865 DQ890756 ABM81682 DQ891811 ABM82737 DQ893920 ABM84846 LN680437 CEJ95640 X69398 CAA49196 Z25521 CAA80977 XM_005247908 XP_005247965 XM_005247909 XP_005247966 XR_241521 XR_241522 XR_924218 XR_924219 XR_924220 NM_001777 NP_001768 NM_198793 NP_942088 NM_001025079 NM_001025080
Function	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. {ECO:0000250, ECO:0000269|PubMed:11509594, ECO:0000269|PubMed:15383453, ECO:0000269|PubMed:7691831}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:7691831}; Multi-pass membrane protein {ECO:0000269|PubMed:7691831}.
Tissue Specificity	Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.
Top Pathways	ECM-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MER6 Gene - orb142364 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CD47-cDNA-Clone - DC02842 from Abgent, a WuXi AppTec company Prices $411.75 Sizes 10 µg Species Human Accession BC010016

Human CD47 Gene ORF cDNA clone in cloning vector - HG12283-G from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12283-ACR from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid - HG12283-UT from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-His tag - HG12283-CH from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12283-ACG from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12283-NF from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12283-NM from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12283-CY from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12283-CF from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid - HG12283-G-N from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12283-CM from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12283-NY from Sino Biological Species Human

Human CD47 Gene ORF cDNA clone expression plasmid, N-His tag - HG12283-NH from Sino Biological Species Human

Human CD47 (NP_001768) VersaClone cDNA - RDC1523 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human CD47 ORF Clone(NM_001777.3) - CDCR281497 from Creative biogene Species Human

Human CD47 ORF Clone(NM_198793.2) - CDCR326219 from Creative biogene Species Human

Human CD47 ORF Clone (BC010016) - CDCS410430 from Creative biogene Species Human Accession Q08722

Human CD47 ORF clone (BC010016) - CDCB157447 from Creative biogene Species Human

Human CD47 ORF clone (BC010016) - CDCB160152 from Creative biogene Species Human

Human CD47 cDNA Clone(NM_198793.2) - CDFG012745 from Creative biogene Species Human

Human CD47 cDNA Clone(NM_001777.3) - CDFH003127 from Creative biogene Species Human

Cynomolgus Monkey CD47 (XP_015301971) VersaClone cDNA - RDC1832 from R&D Systems Prices $199.00 Sizes 10 µg Species Monkey

Mouse CD47 (NP_034711) VersaClone cDNA - RDC2230 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Search more